Klebsiella pneumoniae strain EuSCAPE_ME014

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ME014 is a Gram-negative, rod-shaped bacterium that exhibits a range of traits pertinent to its ecological and pathogenic nature. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is chemoheterotrophic, deriving its energy from organic compounds, and has a complex cell arrangement, appearing in chains, pairs, and as single cells. The strain is motile, possessing flagella, and is adapted to mesophilic conditions, with an optimal growth temperature of 37°C. It has a biotic relationship characterized as free-living, indicating its ability to persist outside of host organisms. EuSCAPE_ME014 is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other metazoans, indicating its potential for cross-species transmission. The health impacts of this strain are significant, as it is associated with a variety of serious infections, including bacteremia, urinary tract infections, pneumonia, and sepsis. These clinical manifestations highlight its pathogenic potential in humans and other animals. In conclusion, the ecological versatility and pathogenic capabilities of Klebsiella pneumoniae strain EuSCAPE_ME014 underscore its importance in both clinical microbiology and public health. Its ability to infect multiple hosts and cause a wide range of serious health conditions makes it a notable subject of study for understanding antimicrobial resistance and infection control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ME014

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ME014
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ME014 genome assembly,

Gene Summary

Adenine Count

1247818 bp

Thymine Count

1251305 bp

Guanine Count

1640611 bp

Cytosine Count

1628007 bp

Genome Length

5767741 bp

Protein-coding Genes

5196 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
molybdopterin-guanine dinucleotide biosynthesis protein mobaSAMEA3538556_04374Not AvailableNegative4667585 - 466816621573.0
protein yihdSAMEA3538556_04375Not AvailablePositive4668238 - 466850710323.5
yihe proteinSAMEA3538556_04376Not AvailablePositive4668583 - 466956938330.6
periplasmic thiol:disulfide interchange protein dsbaSAMEA3538556_04377Not AvailablePositive4669597 - 467022022946.6
putative acyltransferaseSAMEA3538556_04378Not AvailableNegative4670335 - 467116832123.9
dna polymerase iSAMEA3538556_04379Not AvailablePositive4671565 - 4674357103247.0
gtp-binding protein engbSAMEA3538556_04380Not AvailableNegative4674705 - 467533723533.3
gtpase activatorSAMEA3538556_04381Not AvailablePositive4675921 - 467642718780.9
coproporphyrinogen iii oxidaseSAMEA3538556_04382Not AvailablePositive4676616 - 467798952182.3
uncharacterised proteinSAMEA3538556_04383Not AvailableNegative4678025 - 46781353539.33

Displaying genes 4421 – 4430 of 5454 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total