Klebsiella pneumoniae strain EuSCAPE_ME014

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ME014 is a Gram-negative, rod-shaped bacterium that exhibits a range of traits pertinent to its ecological and pathogenic nature. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is chemoheterotrophic, deriving its energy from organic compounds, and has a complex cell arrangement, appearing in chains, pairs, and as single cells. The strain is motile, possessing flagella, and is adapted to mesophilic conditions, with an optimal growth temperature of 37°C. It has a biotic relationship characterized as free-living, indicating its ability to persist outside of host organisms. EuSCAPE_ME014 is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other metazoans, indicating its potential for cross-species transmission. The health impacts of this strain are significant, as it is associated with a variety of serious infections, including bacteremia, urinary tract infections, pneumonia, and sepsis. These clinical manifestations highlight its pathogenic potential in humans and other animals. In conclusion, the ecological versatility and pathogenic capabilities of Klebsiella pneumoniae strain EuSCAPE_ME014 underscore its importance in both clinical microbiology and public health. Its ability to infect multiple hosts and cause a wide range of serious health conditions makes it a notable subject of study for understanding antimicrobial resistance and infection control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ME014

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ME014
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ME014 genome assembly,

Gene Summary

Adenine Count

1247818 bp

Thymine Count

1251305 bp

Guanine Count

1640611 bp

Cytosine Count

1628007 bp

Genome Length

5767741 bp

Protein-coding Genes

5196 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphatase yqabSAMEA3538556_03470Not AvailablePositive3707866 - 370843220692.9
membrane proteinSAMEA3538556_03471Not AvailablePositive3708429 - 370885715483.4
glutamate--cysteine ligaseSAMEA3538556_03472Not AvailablePositive3708924 - 371048058088.3
s-ribosylhomocysteine lyaseSAMEA3538556_03473Not AvailablePositive3710637 - 371115219455.4
arac family transcriptional regulatorSAMEA3538556_03474Not AvailablePositive3711205 - 371197228444.3
2-isopropylmalate synthaseSAMEA3538556_03475Not AvailableNegative3711951 - 371362762691.1
multidrug resistance protein bSAMEA3538556_03476Not AvailableNegative3713764 - 371530255669.6
multidrug resistance secretion proteinSAMEA3538556_03477Not AvailableNegative3715318 - 371649042588.0
transcription repressorSAMEA3538556_03478Not AvailableNegative3716616 - 371714620568.7
branched-chain amino acid transporter azldSAMEA3538556_03479Not AvailableNegative3717237 - 371757211866.9

Displaying genes 3571 – 3580 of 5454 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total