Klebsiella pneumoniae strain EuSCAPE_ME011

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ME011 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe and utilizes a chemoheterotrophic energy source. It typically exists in chains, pairs, or as single cells, and thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. K. pneumoniae EuSCAPE_ME011 is primarily associated with hosts such as Homo sapiens and various animal species, including Gallus gallus, Canis lupus familiaris, and Sus scrofa, among others. Its biotic relationship is characterized as free-living, although it is known to cause a range of serious health effects in humans. Notably, this strain is implicated in conditions such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The extensive list of health effects also includes neonatal sepsis and pulmonary infections, highlighting its pathogenic potential. The bacterium has a single replicon and possesses two membranes, which is typical of Gram-negative bacteria. As a non-sporulating organism, K. pneumoniae EuSCAPE_ME011 relies on its ability to adapt to different environments and hosts for survival and transmission. Its diverse host range and significant health impacts emphasize the ecological importance of this strain in both human and animal health, necessitating ongoing surveillance and research to mitigate its pathogenic effects.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ME011

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ME011
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ME011 genome assembly,

Gene Summary

Adenine Count

1273745 bp

Thymine Count

1258056 bp

Guanine Count

1618611 bp

Cytosine Count

1687091 bp

Genome Length

5837503 bp

Protein-coding Genes

5351 genes

Non-Coding Genes

144 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inner membrane metabolite transport protein yhjeSAMEA3538553_04144Not AvailablePositive4462499 - 446382147002.7
asma family proteinSAMEA3538553_04145Not AvailableNegative4463859 - 446591074341.7
ketodeoxygluconokinaseSAMEA3538553_04146Not AvailablePositive4466105 - 446703433957.1
protein yhjj, putative peptidaseSAMEA3538553_04147Not AvailableNegative4467089 - 446859155774.5
aerobic c4-dicarboxylate transporterSAMEA3538553_04148Not AvailableNegative4468811 - 447009745373.0
protein yhjkSAMEA3538553_04149Not AvailableNegative4470254 - 447226074908.2
cellulose synthase operon protein cSAMEA3538553_04150Not AvailableNegative4472503 - 4475982127110.0
endoglucanaseSAMEA3538553_04151Not AvailableNegative4475964 - 447707040762.1
cellulose synthase regulator proteinSAMEA3538553_04152Not AvailableNegative4477074 - 447939885149.3
cellulose synthase catalytic subunitSAMEA3538553_04153Not AvailableNegative4479430 - 448204899289.2

Displaying genes 4151 – 4160 of 5495 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total