Klebsiella pneumoniae strain EuSCAPE_IL076

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL076 is a facultative anaerobic, Gram-negative bacterium characterized by its rod-shaped morphology and the presence of flagella, which contribute to its mobility. This strain is chemoheterotrophic, deriving energy from organic compounds, and exhibits a mesophilic growth preference, with an optimal temperature of 37°C. It is typically found in host-associated environments, indicating a close relationship with various hosts. Notably, EuSCAPE_IL076 has a wide range of hosts, including Homo sapiens, Gallus gallus, and various other vertebrate species such as Sus scrofa and Canis lupus familiaris. This broad host range suggests that the strain may have evolved mechanisms to adapt to different biological environments, enhancing its survival and pathogenic potential. The strain is associated with a plethora of health effects, including but not limited to bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. Such a diverse array of pathogenic outcomes underlines its role as a significant human pathogen. The strain does not form spores, which is typical for many Enterobacteriaceae, and it has a single replicon with two membranes, indicative of its Gram-negative classification. Biologically, the presence of Klebsiella pneumoniae strain EuSCAPE_IL076 in various hosts highlights the importance of understanding its ecology and pathogenicity. Its adaptability and potential for causing severe infections underscore the need for ongoing surveillance and research to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL076

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL076
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL076 genome assembly,

Gene Summary

Adenine Count

1200714 bp

Thymine Count

1204292 bp

Guanine Count

1601133 bp

Cytosine Count

1613507 bp

Genome Length

5619646 bp

Protein-coding Genes

5053 genes

Non-Coding Genes

376 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetoin:dcpip oxidoreductase beta subunitSAMEA3538533_04817Not AvailablePositive5030893 - 503191236560.1
dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexSAMEA3538533_04818Not AvailablePositive5031916 - 503345154294.1
dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complexSAMEA3538533_04819Not AvailablePositive5033441 - 503483849543.6
zn-finger proteinSAMEA3538533_04820Not AvailablePositive5035015 - 50352669133.67
putative phospho-2-dehydro-3-deoxyheptonate aldolaseSAMEA3538533_04821Not AvailablePositive5035780 - 503657128214.8
glycerol uptake operon antiterminator regulatory proteinSAMEA3538533_04822Not AvailablePositive5036586 - 503713720396.0
putative l-xylulose kinaseSAMEA3538533_04823Not AvailablePositive5037158 - 503869657194.0
3-oxoacyl-acp reductaseSAMEA3538533_04824Not AvailablePositive5038708 - 503946927625.3
d-3-phosphoglycerate dehydrogenaseSAMEA3538533_04825Not AvailablePositive5039486 - 504048136346.6
pts system proteinSAMEA3538533_04826Not AvailablePositive5040570 - 504183245091.0

Displaying genes 4901 – 4910 of 5429 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total