Klebsiella pneumoniae strain EuSCAPE_IL076

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL076 is a facultative anaerobic, Gram-negative bacterium characterized by its rod-shaped morphology and the presence of flagella, which contribute to its mobility. This strain is chemoheterotrophic, deriving energy from organic compounds, and exhibits a mesophilic growth preference, with an optimal temperature of 37°C. It is typically found in host-associated environments, indicating a close relationship with various hosts. Notably, EuSCAPE_IL076 has a wide range of hosts, including Homo sapiens, Gallus gallus, and various other vertebrate species such as Sus scrofa and Canis lupus familiaris. This broad host range suggests that the strain may have evolved mechanisms to adapt to different biological environments, enhancing its survival and pathogenic potential. The strain is associated with a plethora of health effects, including but not limited to bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. Such a diverse array of pathogenic outcomes underlines its role as a significant human pathogen. The strain does not form spores, which is typical for many Enterobacteriaceae, and it has a single replicon with two membranes, indicative of its Gram-negative classification. Biologically, the presence of Klebsiella pneumoniae strain EuSCAPE_IL076 in various hosts highlights the importance of understanding its ecology and pathogenicity. Its adaptability and potential for causing severe infections underscore the need for ongoing surveillance and research to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL076

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL076
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL076 genome assembly,

Gene Summary

Adenine Count

1200714 bp

Thymine Count

1204292 bp

Guanine Count

1601133 bp

Cytosine Count

1613507 bp

Genome Length

5619646 bp

Protein-coding Genes

5053 genes

Non-Coding Genes

376 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3538533_01937Not AvailablePositive2012931 - 20130715401.79
arac family transcriptional regulatorSAMEA3538533_01938Not AvailablePositive2013053 - 201399435559.7
gluconate permeaseSAMEA3538533_01939Not AvailableNegative2014021 - 201538546962.6
hydroxypyruvate isomeraseSAMEA3538533_01940Not AvailableNegative2015443 - 201622529260.0
ribulose-5-phosphate 4-epimeraseSAMEA3538533_01941Not AvailableNegative2016230 - 201685022627.1
ygbk domain proteinSAMEA3538533_01942Not AvailableNegative2016843 - 201810844984.8
ygbjSAMEA3538533_01943Not AvailableNegative2018120 - 201902230480.9
deor family transcriptional regulatorSAMEA3538533_01944Not AvailablePositive2019283 - 202004427339.8
beta-lactamaseSAMEA3538533_01945Not AvailableNegative2020065 - 202092531240.8
putative k+ transporting atpase, kdpc subunitSAMEA3538533_01946Not AvailablePositive2021223 - 20214839393.32

Displaying genes 2091 – 2100 of 5429 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total