Klebsiella pneumoniae strain EuSCAPE_ME001

Klebsiella pneumoniae strain EuSCAPE_ME001 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism as a chemoheterotroph. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles. It possesses flagella, which contribute to its mobility, allowing it to navigate its host-associated habitats. EuSCAPE_ME001 has an optimal growth temperature of 37°C, fitting within the mesophilic temperature range. The bacterium features a unique cellular structure with two membranes and a single replicon, indicating its genetic stability. This strain is notably pathogenic to humans, being associated with multiple serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis. It can cause a wide array of conditions such as cystitis, intra-abdominal infections, liver abscesses, and neonatal sepsis, underscoring its clinical significance. Additionally, it has been linked to infections in various hosts including domesticated animals and other metazoans, highlighting its ecological versatility. The presence of Klebsiella pneumoniae EuSCAPE_ME001 in diverse habitats and its capacity to infect a range of host species suggest a complex ecological role. Its adaptability and pathogenic potential pose significant challenges in clinical settings, particularly regarding infection control and antibiotic resistance. Understanding the biological characteristics of this strain is crucial for developing effective strategies to manage infections it may cause.