Klebsiella pneumoniae strain EuSCAPE_IL029

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL029 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is typically found in host-associated environments and exhibits mobility, propelled by the presence of flagella. It can exist in various cell arrangements, including chains, pairs, and singles. EuSCAPE_IL029 thrives optimally at 37°C, classifying it as mesophilic, and possesses a single replicon with a double membrane structure. This bacterium is known to have a free-living biotic relationship with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoan and plant species. Clinically, Klebsiella pneumoniae strain EuSCAPE_IL029 is associated with several serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and a variety of intra-abdominal infections. Its pathogenicity is notable, as it can lead to severe conditions such as sepsis, neonatal sepsis, and endophthalmitis, making it a significant concern in healthcare settings. Understanding the ecological role of Klebsiella pneumoniae strain EuSCAPE_IL029 is crucial, particularly in relation to its pathogenicity and ability to adapt to various host environments. Its association with both human and animal hosts highlights its potential for zoonotic transmission and raises important considerations for public health and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL029

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL029
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL029 genome assembly,

Gene Summary

Adenine Count

1223549 bp

Thymine Count

1227097 bp

Guanine Count

1638617 bp

Cytosine Count

1621175 bp

Genome Length

5710438 bp

Protein-coding Genes

5135 genes

Non-Coding Genes

401 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cyclic diguanylate phosphodiesterase (eal) domain-containing proteinSAMEA3538487_04842Not AvailableNegative5040928 - 504176431918.5
putative outer membrane or exportedSAMEA3538487_04843Not AvailablePositive5044277 - 50445168421.49
transcriptional regulator kdgrSAMEA3538487_04844Not AvailableNegative5044573 - 504536429980.0
transport proteinSAMEA3538487_04845Not AvailablePositive5045542 - 504691247817.2
heat shock protein htpxSAMEA3538487_04846Not AvailableNegative5046978 - 504786232048.5
carboxy-terminal proteaseSAMEA3538487_04847Not AvailableNegative5048098 - 505014676674.3
proq: influences osmotic activation of compatible solute propSAMEA3538487_04848Not AvailableNegative5050166 - 505084324976.0
free methionine-r-sulfoxide reductaseSAMEA3538487_04849Not AvailableNegative5050941 - 505149520135.2
membrane proteinSAMEA3538487_04850Not AvailablePositive5051571 - 505285447893.0
paraquat-inducible protein bSAMEA3538487_04851Not AvailablePositive5052823 - 505545694809.7

Displaying genes 4891 – 4900 of 5536 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total