Klebsiella pneumoniae strain EuSCAPE_IL029

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL029 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is typically found in host-associated environments and exhibits mobility, propelled by the presence of flagella. It can exist in various cell arrangements, including chains, pairs, and singles. EuSCAPE_IL029 thrives optimally at 37°C, classifying it as mesophilic, and possesses a single replicon with a double membrane structure. This bacterium is known to have a free-living biotic relationship with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoan and plant species. Clinically, Klebsiella pneumoniae strain EuSCAPE_IL029 is associated with several serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and a variety of intra-abdominal infections. Its pathogenicity is notable, as it can lead to severe conditions such as sepsis, neonatal sepsis, and endophthalmitis, making it a significant concern in healthcare settings. Understanding the ecological role of Klebsiella pneumoniae strain EuSCAPE_IL029 is crucial, particularly in relation to its pathogenicity and ability to adapt to various host environments. Its association with both human and animal hosts highlights its potential for zoonotic transmission and raises important considerations for public health and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL029

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL029
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL029 genome assembly,

Gene Summary

Adenine Count

1223549 bp

Thymine Count

1227097 bp

Guanine Count

1638617 bp

Cytosine Count

1621175 bp

Genome Length

5710438 bp

Protein-coding Genes

5135 genes

Non-Coding Genes

401 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
beta-lactamaseSAMEA3538487_03536Not AvailablePositive3683185 - 368394327918.6
membrane proteinSAMEA3538487_03537Not AvailableNegative3683965 - 368433314526.5
histidine kinaseSAMEA3538487_03538Not AvailableNegative3684389 - 368667483574.1
ribose abc transporter atp-binding protein rbsaSAMEA3538487_03539Not AvailablePositive3686854 - 368837455103.4
ribose abc transporter permease rbscSAMEA3538487_03540Not AvailablePositive3688371 - 368936934548.5
ribose abc transport system, periplasmic ribose-binding protein rbsbSAMEA3538487_03541Not AvailablePositive3689400 - 369034132621.3
kinaseSAMEA3538487_03542Not AvailablePositive3690416 - 369142336606.0
nucleotidyl transferase of uncharacterised function (duf1814)SAMEA3538487_03543Not AvailableNegative3691548 - 369246534689.1
protein of unknwon function (duf2893)SAMEA3538487_03544Not AvailableNegative3692471 - 369322928566.4
response regulator proteinSAMEA3538487_03545Not AvailableNegative3693315 - 369404326373.0

Displaying genes 3651 – 3660 of 5536 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total