Klebsiella pneumoniae strain EuSCAPE_IL080

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL080 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. It typically exists in various arrangements, including chains, pairs, and singles. This strain is characterized by its mobility, attributed to the presence of flagella. It thrives optimally at a temperature of 37°C, falling within the mesophilic temperature range. This bacterium has a significant biotic relationship with multiple hosts, including Homo sapiens, various birds (Phasianidae, Aves), mammals (Canis lupus familiaris, Sus scrofa, Equidae), and other organisms like Danio rerio and Viridiplantae. Its pathogenicity primarily affects humans, leading to a spectrum of serious health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The extensive list of infections associated with this strain highlights its potential as a significant public health concern. Klebsiella pneumoniae strain EuSCAPE_IL080 does not form spores and possesses a single replicon and two membranes. Its ability to inhabit diverse hosts and cause a wide range of infections indicates its ecological versatility and adaptability. The strain's presence in both free-living and host-associated environments suggests an intricate role in microbial ecosystems, possibly impacting host health and contributing to the dynamics of infectious diseases. This adaptability underscores the importance of monitoring such strains, particularly given their potential to cause serious infections in various host species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL080

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL080
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL080 genome assembly,

Gene Summary

Adenine Count

1209597 bp

Thymine Count

1217095 bp

Guanine Count

1623773 bp

Cytosine Count

1610299 bp

Genome Length

5660764 bp

Protein-coding Genes

5096 genes

Non-Coding Genes

383 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fimbrial usher family proteinSAMEA3538537_03898Not AvailableNegative4051938 - 405451793614.2
pili assembly chaperoneSAMEA3538537_03899Not AvailableNegative4054471 - 405516025206.4
fimbrial subunitSAMEA3538537_03900Not AvailableNegative4055221 - 405576018406.3
cida-associated membrane protein cidbSAMEA3538537_03901Not AvailableNegative4056289 - 405697824602.0
lrga family proteinSAMEA3538537_03902Not AvailableNegative4056975 - 405738215182.6
lysr family regulatory protein cidrSAMEA3538537_03903Not AvailablePositive4057488 - 405836933318.7
na(+)/h(+) exchanger proteinSAMEA3538537_03904Not AvailableNegative4058532 - 406017860108.9
guanine-hypoxanthine permeaseSAMEA3538537_03905Not AvailableNegative4060326 - 406167545666.4
glutathione s-transferaseSAMEA3538537_03906Not AvailableNegative4062064 - 406273225136.8
redox-sensitive transcriptional activator soxrSAMEA3538537_03907Not AvailableNegative4062992 - 406345016971.6

Displaying genes 4001 – 4010 of 5479 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total