Klebsiella pneumoniae strain EuSCAPE_IL079

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL079 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism, allowing it to thrive in varying oxygen conditions. This strain is classified as a chemoheterotroph, deriving energy from organic compounds. It can be found in different arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. EuSCAPE_IL079 has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the typical body temperature of its primary host, Homo sapiens. This strain is known to have a significant pathogenicity towards humans and is associated with various health complications, including bacteremia, urinary tract infections, pneumonia, and sepsis. It is also implicated in both neonatal and adult infections, such as pyogenic liver abscesses and abdominal infections, demonstrating its clinical relevance. The bacterium has been identified as free-living in some contexts, yet it is also closely associated with multiple hosts, including Gallus gallus, Canis lupus familiaris, and various other vertebrates and invertebrates. This wide host range may facilitate its transmission and adaptability in diverse environments. Understanding the ecological niche and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_IL079 is crucial, particularly in a clinical setting, as it highlights the importance of monitoring and controlling infections caused by this adaptable organism, especially in healthcare environments where vulnerable populations are present.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL079

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL079
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL079 genome assembly,

Gene Summary

Adenine Count

1217260 bp

Thymine Count

1221101 bp

Guanine Count

1642481 bp

Cytosine Count

1609326 bp

Genome Length

5690168 bp

Protein-coding Genes

5042 genes

Non-Coding Genes

473 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-glyNot AvailableNot AvailablePositive5631687 - 5631761Not Available
Trna-tyrNot AvailableNot AvailablePositive5631877 - 5631961Not Available
Trna-thrNot AvailableNot AvailablePositive5631972 - 5632047Not Available
pantothenate kinaseSAMEA3538536_05450Not AvailablePositive5632500 - 563342635283.4
biotin--protein ligaseSAMEA3538536_05451Not AvailableNegative5633452 - 563441435433.9
udp-n-acetylenolpyruvoylglucosamine reductaseSAMEA3538536_05452Not AvailableNegative5634411 - 563543937825.2
flagellar biosynthesis, cell-distal portion of basal-body rodSAMEA3538536_05454Not AvailablePositive5636366 - 563830971206.5
uncharacterised proteinSAMEA3538536_05455Not AvailablePositive5638317 - 56384424462.57
uncharacterised proteinSAMEA3538536_05456Not AvailablePositive5638551 - 563915021539.5
uncharacterised proteinSAMEA3538536_05457Not AvailableNegative5639184 - 56393787498.77

Displaying genes 5471 – 5480 of 5515 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total