Klebsiella pneumoniae strain EuSCAPE_IL028

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL028 is a Gram-negative, mesophilic, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and is classified as a chemoheterotroph. This strain typically resides in host-associated environments and is capable of mobility due to the presence of flagella. It can be found in various arrangements, including chains, pairs, and singles. This strain has been implicated in numerous health issues, particularly in humans, where it can cause serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. Other health effects include intra-abdominal infections, liver abscesses, meningitis, and wound infections. K. pneumoniae is associated with both community-acquired and hospital-acquired infections, making it a significant pathogen in clinical settings. K. pneumoniae strain EuSCAPE_IL028 has a single replicon and a double membrane structure, which is characteristic of its classification within the Enterobacteriaceae family. Its broad range of hosts includes various species such as Homo sapiens, Gallus gallus, and Canis lupus familiaris, indicating its adaptability and potential for cross-species transmission. The ability of K. pneumoniae to thrive in diverse environments and its pathogenic potential highlight its ecological significance. This strain exemplifies the challenges in managing infections caused by opportunistic pathogens, especially in immunocompromised individuals, and underscores the importance of understanding its biology in developing effective therapeutic strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL028

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL028
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL028 genome assembly,

Gene Summary

Adenine Count

1143791 bp

Thymine Count

1140458 bp

Guanine Count

1533535 bp

Cytosine Count

1534258 bp

Genome Length

5352042 bp

Protein-coding Genes

4918 genes

Non-Coding Genes

129 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3538486_03376Not AvailableNegative3593564 - 35938038761.6
pyridoxal kinaseSAMEA3538486_03377Not AvailableNegative3593800 - 359466631223.4
transcriptional regulator of pyridoxine metabolismSAMEA3538486_03378Not AvailablePositive3594749 - 359604746422.6
yybh proteinSAMEA3538486_03379Not AvailablePositive3596188 - 359658314652.5
cysteine synthase bSAMEA3538486_03380Not AvailableNegative3596580 - 359749132616.1
sulfate and thiosulfate import atp-binding protein cysaSAMEA3538486_03381Not AvailableNegative3597610 - 359870440844.3
sulfate transport system permease protein cyswSAMEA3538486_03382Not AvailableNegative3598694 - 359956932288.3
sulfate transport system permease protein cystSAMEA3538486_03383Not AvailableNegative3599569 - 360040230312.7
sulfate and thiosulfate binding protein cyspSAMEA3538486_03384Not AvailableNegative3600402 - 360141837558.6
iron-dependent peroxidaseSAMEA3538486_03385Not AvailableNegative3602058 - 360295733091.1

Displaying genes 3381 – 3390 of 5047 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total