Klebsiella pneumoniae strain EuSCAPE_IL068

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL068 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, enabling it to thrive in varying oxygen environments. It is characterized by its ability to form chains, pairs, and singles, and possesses flagella, contributing to its mobility. This strain is a chemoheterotroph, deriving energy from organic compounds, and is mesophilic, with an optimal growth temperature of 37°C. The ecological niche of K. pneumoniae EuSCAPE_IL068 is host-associated, indicating a relationship with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants. This bacterium is known for its pathogenicity, particularly in humans, where it is implicated in a range of serious health effects including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The diverse range of infections it can cause highlights its clinical significance and the potential for severe health implications. K. pneumoniae EuSCAPE_IL068 does not undergo sporulation and contains a single replicon within its structure, surrounded by two membranes typical of Gram-negative bacteria. Its free-living biotic relationship allows it to persist in various environments, potentially contributing to its role as a pathogen in both human and veterinary medicine. The wide host range and variety of infections associated with K. pneumoniae EuSCAPE_IL068 underscore its adaptability and potential impact on health, reinforcing the importance of monitoring and understanding such pathogens in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL068

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL068
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL068 genome assembly,

Gene Summary

Adenine Count

1171810 bp

Thymine Count

1180142 bp

Guanine Count

1589998 bp

Cytosine Count

1549098 bp

Genome Length

5491048 bp

Protein-coding Genes

4942 genes

Non-Coding Genes

240 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
zinc abc transporterSAMEA3538525_00578Not AvailableNegative653506 - 65425827603.1
high-affinity zinc transporter periplasmic componentSAMEA3538525_00579Not AvailablePositive654337 - 65528134078.6
cell wall endopeptidaseSAMEA3538525_00580Not AvailablePositive655297 - 65661648948.3
lipid a biosynthesis (kdo) 2-(lauroyl)-lipid iva acyltransferaseSAMEA3538525_00581Not AvailablePositive656734 - 65770837455.8
pyruvate kinaseSAMEA3538525_00582Not AvailableNegative657749 - 65919151425.2
phosphogluconate repressor hexr, rpir familySAMEA3538525_00583Not AvailableNegative659317 - 66020432616.2
glucose-6-phosphate 1-dehydrogenaseSAMEA3538525_00584Not AvailablePositive660542 - 66201755874.7
phosphogluconate dehydrataseSAMEA3538525_00585Not AvailablePositive662240 - 66405164571.0
4-hydroxy-2-ketovalerate aldolaseSAMEA3538525_00586Not AvailablePositive664090 - 66473122230.1
phosphoribosylglycinamide formyltransferaseSAMEA3538525_00587Not AvailableNegative664789 - 66596741982.5

Displaying genes 751 – 760 of 5182 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total