Klebsiella pneumoniae strain EuSCAPE_IL068

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL068 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, enabling it to thrive in varying oxygen environments. It is characterized by its ability to form chains, pairs, and singles, and possesses flagella, contributing to its mobility. This strain is a chemoheterotroph, deriving energy from organic compounds, and is mesophilic, with an optimal growth temperature of 37°C. The ecological niche of K. pneumoniae EuSCAPE_IL068 is host-associated, indicating a relationship with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants. This bacterium is known for its pathogenicity, particularly in humans, where it is implicated in a range of serious health effects including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The diverse range of infections it can cause highlights its clinical significance and the potential for severe health implications. K. pneumoniae EuSCAPE_IL068 does not undergo sporulation and contains a single replicon within its structure, surrounded by two membranes typical of Gram-negative bacteria. Its free-living biotic relationship allows it to persist in various environments, potentially contributing to its role as a pathogen in both human and veterinary medicine. The wide host range and variety of infections associated with K. pneumoniae EuSCAPE_IL068 underscore its adaptability and potential impact on health, reinforcing the importance of monitoring and understanding such pathogens in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL068

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL068
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL068 genome assembly,

Gene Summary

Adenine Count

1171810 bp

Thymine Count

1180142 bp

Guanine Count

1589998 bp

Cytosine Count

1549098 bp

Genome Length

5491048 bp

Protein-coding Genes

4942 genes

Non-Coding Genes

240 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
universal stress protein uspbSAMEA3538525_03270Not AvailablePositive3499220 - 349955512976.1
low-affinity inorganic phosphate transporterSAMEA3538525_03271Not AvailableNegative3499611 - 350110753364.4
oxidoreductaseSAMEA3538525_03272Not AvailablePositive3501382 - 350253042173.7
magnesium transporterSAMEA3538525_03273Not AvailableNegative3502570 - 350358337087.6
uncharacterized protein encoded in hypervariable junctions of pilus gene clustersSAMEA3538525_03274Not AvailablePositive3503990 - 350434913341.8
nickel responsive regulator nikrSAMEA3538525_03275Not AvailableNegative3504377 - 350477815029.6
nickel transport atp-binding protein nikeSAMEA3538525_03276Not AvailableNegative3504766 - 350555728742.5
nickel transport atp-binding protein nikdSAMEA3538525_03277Not AvailableNegative3505554 - 350631827281.7
nickel transport system permease protein nikcSAMEA3538525_03278Not AvailableNegative3506318 - 350715130183.8
nickel transport system permease protein nikbSAMEA3538525_03279Not AvailableNegative3507148 - 350809235303.4

Displaying genes 3381 – 3390 of 5182 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total