Klebsiella pneumoniae strain EuSCAPE_IL063

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL063 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. It typically thrives in host-associated habitats, demonstrating a versatile biotic relationship as a free-living organism. This strain is capable of existing in various forms, including chains, pairs, and singles, and possesses flagella, contributing to its mobility. The optimal growth temperature for EuSCAPE_IL063 is 37°C, placing it within the mesophilic range. It has a single replicon and two membranes, characteristic of its Gram-negative classification. This strain is known to infect a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various mammals, amphibians, and plants. Clinically, Klebsiella pneumoniae strain EuSCAPE_IL063 is associated with numerous health complications, including bacteremia, urinary tract infections, pneumonia, and several other serious infections such as meningitis and sepsis. Its pathogenicity is primarily noted in humans, but it also poses risks to various animal species. The breadth of hosts and the extensive range of infections highlight the ecological adaptability and potential zoonotic implications of this strain. Understanding its pathogenic mechanisms and host interactions is crucial for developing effective prevention and treatment strategies, particularly in healthcare settings where multidrug-resistant strains are a growing concern.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL063

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL063
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL063 genome assembly,

Gene Summary

Adenine Count

1227547 bp

Thymine Count

1228315 bp

Guanine Count

1645811 bp

Cytosine Count

1620171 bp

Genome Length

5721844 bp

Protein-coding Genes

5145 genes

Non-Coding Genes

402 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3538520_01296Not AvailablePositive1340854 - 134127615668.7
Virion morphogenesis proteinSAMEA3538520_01297Not AvailablePositive1341269 - 134171517329.9
Hypothetical proteinSAMEA3538520_01298Not AvailableNegative1341738 - 134260433195.7
Baseplate assembly protein vSAMEA3538520_01299Not AvailablePositive1342699 - 134327120638.2
Baseplate assembly proteinSAMEA3538520_01300Not AvailablePositive1343268 - 134363013333.1
Baseplate assembly protein jSAMEA3538520_01301Not AvailablePositive1343617 - 134452532845.6
Tail protein iSAMEA3538520_01302Not AvailablePositive1344566 - 134518923281.1
Spore coat proteinSAMEA3538520_01303Not AvailablePositive1345191 - 134661851984.3
Spore coat proteinSAMEA3538520_01304Not AvailablePositive1346664 - 134714018580.1
Hypothetical proteinSAMEA3538520_01305Not AvailablePositive1347150 - 134826839457.7

Displaying genes 121 – 130 of 5547 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total