Klebsiella pneumoniae strain EuSCAPE_IL045

Klebsiella pneumoniae strain EuSCAPE_IL045 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, primarily functioning as a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, and single cells, and it possesses flagella, indicating motility. Optimally, it thrives at 37°C, within a mesophilic temperature range. This bacterium is primarily host-associated, with a diverse range of potential hosts including Homo sapiens, various domesticated animals such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as certain aquatic species like Danio rerio (zebrafish). Its relationship with these hosts can be described as free-living, suggesting it can exist independently of a host in some environments. Klebsiella pneumoniae strain EuSCAPE_IL045 is notably pathogenic to humans, implicated in a variety of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. This strain is particularly concerning due to its role in neonatal sepsis and other severe infections such as liver abscesses and intra-abdominal infections. The breadth of diseases associated with this strain highlights its clinical significance. The presence of this bacterium in multiple host species suggests an ecological adaptability that may facilitate its transmission and persistence in various environments. Understanding the pathogenicity and ecological interactions of K. pneumoniae strain EuSCAPE_IL045 is crucial for developing effective strategies to manage infections and mitigate its impact on health.