Klebsiella pneumoniae strain EuSCAPE_IL044

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL044 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, categorizing it as a chemoheterotroph. Its optimal growth temperature is 37°C, placing it within the mesophilic range. This strain is characterized by its cell arrangement, which can be observed as chains, pairs, or singles, and it possesses flagella, indicating motility. K. pneumoniae EuSCAPE_IL044 is known for its pathogenicity in humans, causing a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. It can also infect various hosts, such as Homo sapiens, Gallus gallus, and multiple other vertebrates and invertebrates, indicating a broad ecological footprint. The bacterium is nonsporulating and has a biotic relationship that allows for free living. It contains a single replicon and is surrounded by two membranes, typical of its classification within the Enterobacteriaceae family. The ecological significance of K. pneumoniae strain EuSCAPE_IL044 lies in its ability to thrive in diverse environments, affecting both human health and animal species. Its capacity to cause infections across multiple hosts emphasizes the importance of understanding its behavior and transmission dynamics, particularly in clinical settings where antibiotic resistance is a growing concern.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL044

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL044
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL044


Gene Summary

Adenine Count

1215749 bp

Thymine Count

1218906 bp

Guanine Count

1639171 bp

Cytosine Count

1601062 bp

Genome Length

5674888 bp

Protein-coding Genes

5126 genes

Non-Coding Genes

351 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aldo-keto reductaseSAMEA3538500_00476Not AvailableNegative463771 - 46464931476.0
serine transporterSAMEA3538500_00477Not AvailableNegative464768 - 46599744408.9
na(+)-translocating nadh-quinone reductase subunit eSAMEA3538500_00478Not AvailableNegative466121 - 46658217554.1
lysr family transcriptional regulatorSAMEA3538500_00479Not AvailablePositive466685 - 46755431745.0
3-ketoacyl-coa thiolaseSAMEA3538500_00480Not AvailablePositive467673 - 46885141081.2
oligogalacturonate-specific porin protein kdgmSAMEA3538500_00481Not AvailablePositive469100 - 46979526117.9
oligogalacturonate lyaseSAMEA3538500_00482Not AvailableNegative469931 - 47110644106.6
2-deoxy-d-gluconate 3-dehydrogenaseSAMEA3538500_00483Not AvailablePositive471592 - 47235327079.6
arabinose-proton symporterSAMEA3538500_00484Not AvailablePositive472649 - 47407051746.3
sugar-binding domain proteinSAMEA3538500_00485Not AvailableNegative474067 - 47506236293.8

Displaying genes 761 – 770 of 5477 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total