Klebsiella pneumoniae strain EuSCAPE_IL025

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL025 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain exhibits a diverse habitat, primarily associated with various hosts, including Homo sapiens and multiple animal species such as Gallus gallus (chickens), Danio rerio (zebrafish), and Sus scrofa (pigs). It can be found in chains, pairs, or as single cells, and possesses flagella, indicating motility. EuSCAPE_IL025 is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for survival in warm-blooded hosts. It has a unique biotic relationship, being free-living, and is characterized by a single replicon and two membranes. This strain is notable for its pathogenicity in humans, contributing to a spectrum of serious health conditions, including bacteremia, pneumonia, urinary tract infections, and various intra-abdominal infections. It has been implicated in severe complications such as neonatal sepsis and pyogenic liver abscesses, demonstrating its capability to cause significant morbidity. The ecological insight gained from studying Klebsiella pneumoniae EuSCAPE_IL025 highlights the bacterium's adaptability to different environments and hosts, underscoring its role as a prominent opportunistic pathogen. Its presence in a variety of hosts and its association with numerous infections emphasize the importance of monitoring this strain in clinical settings to manage and mitigate its health impacts effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL025

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL025 genome assembly,

Gene Summary

Adenine Count

1181023 bp

Thymine Count

1179178 bp

Guanine Count

1573966 bp

Cytosine Count

1580312 bp

Genome Length

5514479 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
biofilm formation regulatory protein bsssSAMEA3538483_01349Not AvailablePositive1454414 - 14546689737.27
n-methyl-l-tryptophan oxidaseSAMEA3538483_01350Not AvailablePositive1454794 - 145591240350.5
protein of uncharacterised function (duf2770)SAMEA3538483_01351Not AvailablePositive1455984 - 14560974712.08
putative rhodanese-related sulfurtransferaseSAMEA3538483_01352Not AvailableNegative1456083 - 145714740237.0
lipid a biosynthesis (kdo) 2-(lauroyl)-lipid iva acyltransferaseSAMEA3538483_01353Not AvailablePositive1457353 - 145827335542.0
multidrug-efflux transporter, major facilitator superfamily (mfs)SAMEA3538483_01354Not AvailablePositive1458445 - 145967143715.7
acidic protein msybSAMEA3538483_01355Not AvailablePositive1459763 - 146014914763.3
outer membrane lipoproteinSAMEA3538483_01356Not AvailableNegative1460150 - 14603778316.15
glucans biosynthesis glucosyltransferase hSAMEA3538483_01357Not AvailableNegative1460444 - 146297296083.6
glucans biosynthesis protein gSAMEA3538483_01358Not AvailableNegative1462965 - 146451858572.5

Displaying genes 1511 – 1520 of 5228 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total