Klebsiella pneumoniae strain EuSCAPE_IT072

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT072 is a gram-negative, rod-shaped bacterium, notable for its ability to thrive in various host-associated environments. As a facultative anaerobe, it can utilize both aerobic and anaerobic metabolic pathways, functioning as a chemoheterotroph that derives energy from organic compounds. This strain typically exhibits diverse cell arrangements, appearing in chains, pairs, or as singles, and possesses flagella, enabling mobility. The optimal growth temperature for EuSCAPE_IT072 is 37°C, placing it within a mesophilic temperature range, which is consistent with its association with warm-blooded hosts. Its biotic relationships are primarily free-living, yet it has been documented to infect multiple hosts, including Homo sapiens and various animals such as Gallus gallus, Canis lupus familiaris, and Sus scrofa, among others. Clinically, Klebsiella pneumoniae strain EuSCAPE_IT072 is associated with a wide range of serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity is particularly significant in hospital settings, where it can lead to severe infections such as neonatal sepsis and intra-abdominal infections. Understanding the ecological roles and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_IT072 underlines the importance of monitoring this bacterium in both clinical and environmental contexts. Its wide host range and ability to cause various infections underscore the need for vigilant public health measures to manage its impact on human health and animal welfare.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT072

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT072
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT072 genome assembly,

Gene Summary

Adenine Count

1206480 bp

Thymine Count

1202229 bp

Guanine Count

1615417 bp

Cytosine Count

1603449 bp

Genome Length

5627575 bp

Protein-coding Genes

5074 genes

Non-Coding Genes

353 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4fe-4s ferredoxinSAMEA3515102_00471Not AvailablePositive519462 - 5197229769.74
holo-[acyl-carrier protein] synthaseSAMEA3515102_00472Not AvailableNegative519735 - 52011514038.0
pyridoxine 5'-phosphate synthaseSAMEA3515102_00473Not AvailableNegative520115 - 52084626474.0
dna recombination and repair protein recoSAMEA3515102_00474Not AvailableNegative520858 - 52159527435.0
gtp-binding protein eraSAMEA3515102_00475Not AvailableNegative521607 - 52251233885.1
ribonuclease iiiSAMEA3515102_00476Not AvailableNegative522509 - 52318925558.6
signal peptidase iSAMEA3515102_00477Not AvailableNegative523439 - 52441335791.3
translation elongation factor lepaSAMEA3515102_00478Not AvailableNegative524429 - 52622866439.1
sigma factor rpoe regulatory protein rsecSAMEA3515102_00479Not AvailableNegative526414 - 52689316505.2
anti-sigma e factorSAMEA3515102_00480Not AvailableNegative526890 - 52784635196.8

Displaying genes 721 – 730 of 5427 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total