Klebsiella pneumoniae strain EuSCAPE_IT070

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT070 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle and is classified as a chemoheterotroph. It is capable of existing in various arrangements, including chains, pairs, and singles. This strain is motile, possessing flagella, and thrives optimally at a temperature of 37°C, fitting within the mesophilic temperature range. This bacterium is associated with a diverse array of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. Its biotic relationship is characterized as free-living, indicating a certain level of environmental adaptability. However, K. pneumoniae is notably pathogenic to humans, implicated in multiple health complications such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain has a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. The health effects it can cause highlight its clinical significance, especially in vulnerable populations, including neonates, where it can lead to conditions such as early onset neonatal sepsis. The ecological insight into Klebsiella pneumoniae strain EuSCAPE_IT070 emphasizes its role as a potential opportunistic pathogen in both human and animal hosts. Its ability to thrive in various environments and host organisms underscores the importance of monitoring its prevalence and resistance patterns, especially in clinical settings where infections may arise from common sources such as urinary catheters and surgical wounds.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT070

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT070
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT070 genome assembly,

Gene Summary

Adenine Count

1254773 bp

Thymine Count

1256071 bp

Guanine Count

1672424 bp

Cytosine Count

1658169 bp

Genome Length

5841437 bp

Protein-coding Genes

5258 genes

Non-Coding Genes

405 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
[nife] hydrogenase metallocenter assembly protein hypdSAMEA3515100_00346Not AvailableNegative357940 - 35906141336.7
[nife] hydrogenase metallocenter assembly protein hypcSAMEA3515100_00347Not AvailableNegative359061 - 3593339697.72
[nife] hydrogenase nickel incorporation-associated protein hypbSAMEA3515100_00348Not AvailableNegative359324 - 36019631583.8
[nife] hydrogenase nickel incorporation protein hypaSAMEA3515100_00349Not AvailableNegative360200 - 36054412924.5
formate hydrogenlyase regulatory protein hycaSAMEA3515100_00350Not AvailablePositive360754 - 36120317116.2
formate hydrogenlyase subunit 2SAMEA3515100_00351Not AvailablePositive361286 - 36189421849.3
formate hydrogenlyase subunit 3SAMEA3515100_00352Not AvailablePositive361891 - 36371764025.2
formate hydrogenlyase subunit 4SAMEA3515100_00353Not AvailablePositive363720 - 36464332984.5
formate hydrogenlyase subunit 5SAMEA3515100_00354Not AvailablePositive364660 - 36636964973.1
formate hydrogenlyase complex 3 iron-sulfur proteinSAMEA3515100_00355Not AvailablePositive366379 - 36692120521.8

Displaying genes 721 – 730 of 5663 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total