Klebsiella pneumoniae strain EuSCAPE_IT059

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT059 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. This strain is capable of existing in various cell arrangements, including singles, pairs, and chains, and possesses flagella, which contribute to its mobility. EuSCAPE_IT059 has an optimal growth temperature of 37°C, placing it within the mesophilic temperature range. This strain is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans, as well as plants and fish. Its biotic relationship is characterized as free-living, yet it exhibits significant pathogenicity in humans, causing a multitude of health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. These health effects reflect its potential to be a serious opportunistic pathogen, particularly in immunocompromised individuals. Klebsiella pneumoniae strain EuSCAPE_IT059 is notable for its ability to thrive in host-associated environments, which may facilitate its pathogenic interactions. The presence of this strain in diverse hosts underscores its ecological adaptability and potential for transmission across species. Understanding the traits of this strain is vital for developing strategies to manage infections it may cause, particularly in clinical settings where its pathogenicity can lead to severe health outcomes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT059

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT059
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT059 genome assembly,

Gene Summary

Adenine Count

1190042 bp

Thymine Count

1186632 bp

Guanine Count

1580914 bp

Cytosine Count

1592993 bp

Genome Length

5550581 bp

Protein-coding Genes

5042 genes

Non-Coding Genes

202 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
propanediol utilization protein pduvSAMEA3515091_01272Not AvailableNegative1379054 - 137949415782.0
propanediol utilization polyhedral body protein pduuSAMEA3515091_01273Not AvailableNegative1379499 - 137984912459.3
propanediol utilization polyhedral body protein pdutSAMEA3515091_01274Not AvailableNegative1379849 - 138040319009.5
cob(iii)alamin/cob(ii)alamin reductaseSAMEA3515091_01275Not AvailableNegative1380406 - 138175848053.2
propanediol utilization protein pduqSAMEA3515091_01276Not AvailableNegative1381755 - 138286739311.7
coa-acylating propionaldehyde dehydrogenaseSAMEA3515091_01277Not AvailableNegative1382879 - 138426748792.1
cob(i)alamin adenosyltransferase pduoSAMEA3515091_01278Not AvailableNegative1384264 - 138528036912.3
propanediol utilization protein pdunSAMEA3515091_01279Not AvailableNegative1385291 - 13855669336.22
propanediol utilization protein pdumSAMEA3515091_01280Not AvailableNegative1385570 - 138606117710.1
propanediol utilization protein pdulSAMEA3515091_01281Not AvailableNegative1386058 - 138669022706.6

Displaying genes 1411 – 1420 of 5244 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total