Klebsiella pneumoniae strain EuSCAPE_IT050

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT050 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism as a chemoheterotroph. This strain is capable of forming chains, pairs, and singles, and possesses flagella, enabling mobility. It thrives optimally at 37°C and falls within the mesophilic temperature range. The bacterium has a free-living biotic relationship and is characterized by a single replicon and a double membrane structure. Klebsiella pneumoniae is known for its significant health implications, particularly in humans, where it can lead to a variety of serious infections. These include bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. It is also associated with liver abscesses, meningitis, wound infections, and septicemia, among others. Its pathogenicity extends to various hosts, including Homo sapiens, Gallus gallus, and several other species across Metazoa, Viridiplantae, and Aves, indicating its ecological flexibility. The wide host range and variety of infections caused by Klebsiella pneumoniae strain EuSCAPE_IT050 highlight its adaptability and potential as a significant opportunistic pathogen in both clinical and environmental settings. Understanding its traits and pathogenic potential is crucial for developing effective treatment strategies and managing infections arising from this versatile bacterium.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT050

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT050
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT050 genome assembly,

Gene Summary

Adenine Count

1137671 bp

Thymine Count

1135737 bp

Guanine Count

1529844 bp

Cytosine Count

1535229 bp

Genome Length

5338481 bp

Protein-coding Genes

4796 genes

Non-Coding Genes

232 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Translation initiation factor 3SAMEA3515082_00786Not AvailablePositive850720 - 85115416595.4
AttlNot AvailableNot AvailablePositive1517240 - 1517254Not Available
IntegraseSAMEA3515082_01452Not AvailablePositive1526425 - 152752541914.6
Hypothetical proteinSAMEA3515082_01453Not AvailableNegative1527736 - 152801710736.7
CinSAMEA3515082_01454Not AvailableNegative1529064 - 152961220424.7
Tail spike protein head-binding proteinSAMEA3515082_01455Not AvailablePositive1529793 - 153134655223.7
Hypothetical proteinSAMEA3515082_01456Not AvailableNegative1531647 - 15319169749.46
Tail spike proteinSAMEA3515082_01457Not AvailableNegative1531918 - 153402376949.7
Tail proteinSAMEA3515082_01458Not AvailableNegative1534085 - 153646986194.1
Hypothetical proteinSAMEA3515082_01459Not AvailableNegative1537165 - 153754514196.2

Displaying genes 71 – 80 of 5028 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total