Klebsiella pneumoniae strain EuSCAPE_IT051

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT051 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. It typically exists in a host-associated habitat and exhibits a range of cellular arrangements, including chains, pairs, and singles. The bacterium possesses flagella, which contribute to its mobility, and it has a mesophilic temperature range with an optimal growth temperature of 37°C. Klebsiella pneumoniae is known for its pathogenicity in humans, causing a variety of serious health issues. These include bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The strain is also associated with specific conditions such as septicemia, neonatal sepsis, and pyogenic liver abscesses. Its ability to infect a wide range of hosts, including Homo sapiens, Gallus gallus, and various other animals, underscores its ecological versatility and the potential for zoonotic transmission. The bacterium is nonsporulating and contains a single replicon and two membranes, characteristic of its Gram-negative cell structure. Its free-living biotic relationship allows it to thrive in various environments, which may contribute to its role as an opportunistic pathogen. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_IT051 is crucial for public health, given its significant impact on human health and its potential as a pathogen in both clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT051

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT051
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT051 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4591 genes

Non-Coding Genes

626 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l2SAMEA3515083_05032Not AvailableNegative5382050 - 538287129836.2
50s ribosomal protein l23SAMEA3515083_05033Not AvailableNegative5382889 - 538319111213.8
50s ribosomal protein l4SAMEA3515083_05034Not AvailableNegative5383188 - 538379322114.8
50s ribosomal protein l3SAMEA3515083_05035Not AvailableNegative5383804 - 538443322239.8
30s ribosomal protein s10SAMEA3515083_05036Not AvailableNegative5384466 - 538477711767.3
leader peptidase (prepilin peptidase)SAMEA3515083_05037Not AvailablePositive5385068 - 538564621115.8
bacterioferritinSAMEA3515083_05038Not AvailableNegative5385630 - 538610618326.1
bacterioferritin-associated ferredoxinSAMEA3515083_05039Not AvailableNegative5386180 - 53863747410.11
replication proteinSAMEA3515083_05040Not AvailablePositive5387262 - 538801729375.1
conjugal transfer fertility inhibition protein finoSAMEA3515083_05041Not AvailablePositive5389610 - 539017321090.2

Displaying genes 5041 – 5050 of 5217 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total