Klebsiella pneumoniae strain EuSCAPE_IT049

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT049 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is chemoheterotrophic, utilizing organic compounds as an energy source. It typically exists in various cell arrangements, appearing in chains, pairs, and singles. Its optimal growth temperature is 37°C, placing it in the mesophilic range, which is conducive to growth in warm-blooded hosts. EuSCAPE_IT049 exhibits mobility, with flagella present, allowing for movement in its host-associated habitats. This strain has been found in a diverse array of hosts, including Homo sapiens, various birds (Phasianidae, Aves), mammals (such as Sus scrofa and Canis lupus familiaris), and aquatic species like Danio rerio. Its biotic relationship is characterized as free-living, indicating that it can survive outside of host organisms. The pathogenicity of K. pneumoniae strain EuSCAPE_IT049 is significant, as it is associated with numerous health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. These infections can severely impact human health, demonstrating the strain's role as an opportunistic pathogen. Understanding the ecological role of K. pneumoniae strain EuSCAPE_IT049 in both natural and clinical settings highlights its adaptability and potential for causing disease in a variety of hosts, underscoring the importance of monitoring such strains in public health and clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT049

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT049
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT049 genome assembly,

Gene Summary

Adenine Count

1230040 bp

Thymine Count

1224893 bp

Guanine Count

1627384 bp

Cytosine Count

1640709 bp

Genome Length

5723026 bp

Protein-coding Genes

5142 genes

Non-Coding Genes

411 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
prepilin peptidase dependent protein cSAMEA3515081_00526Not AvailableNegative579458 - 57978111998.8
protein of uncharacterised function (duf2509)SAMEA3515081_00527Not AvailableNegative579766 - 58017314765.0
prepilin peptidase dependent protein bSAMEA3515081_00528Not AvailableNegative580170 - 58072719807.8
prepilin peptidase-dependent protein aSAMEA3515081_00529Not AvailableNegative580724 - 58127520563.7
thymidylate synthaseSAMEA3515081_00530Not AvailableNegative581461 - 58225530294.2
prolipoprotein diacylglyceryl transferaseSAMEA3515081_00531Not AvailableNegative582262 - 58313732993.6
phosphocarrier protein kinase/phosphorylaseSAMEA3515081_00532Not AvailableNegative583383 - 58562983510.3
adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolaseSAMEA3515081_00533Not AvailableNegative585642 - 58617220736.9
dna mismatch repair endonuclease muthSAMEA3515081_00534Not AvailablePositive586855 - 58755025467.9
integral membrane protein tercSAMEA3515081_00535Not AvailablePositive587614 - 58832726229.2

Displaying genes 841 – 850 of 5553 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total