Klebsiella pneumoniae strain EuSCAPE_IT047

Klebsiella pneumoniae strain EuSCAPE_IT047 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism as a chemoheterotroph. It is characterized by its ability to grow in various arrangements, including chains, pairs, and singles. This strain is motile, possessing flagella, and thrives optimally at 37°C within a mesophilic temperature range. K. pneumoniae strain EuSCAPE_IT047 is known to have significant pathogenic potential in humans, being associated with multiple health conditions such as bacteremia, urinary tract infections, pneumonia, and a variety of intra-abdominal infections. It is also linked to severe outcomes like sepsis and neonatal sepsis, among others. This bacterium has a broad host range, infecting not only humans (Homo sapiens) but also a variety of other species, including domestic animals and livestock such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as aquatic organisms like Danio rerio (zebrafish). The biotic relationship of K. pneumoniae strain EuSCAPE_IT047 is categorized as free-living, indicating its adaptability to diverse environments including human hosts and various animal species. This adaptability, combined with its pathogenicity, underscores the ecological significance of K. pneumoniae as it contributes to both health challenges in humans and interactions within broader ecological systems. The presence of this strain in diverse hosts highlights the potential for cross-species transmission and raises concerns regarding its management in both clinical and environmental contexts.