Klebsiella pneumoniae strain EuSCAPE_IT042

Klebsiella pneumoniae strain EuSCAPE_IT042 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it capable of thriving in both aerobic and anaerobic environments. It is primarily chemoheterotrophic, relying on organic compounds for energy. This strain typically exists in various cellular arrangements, including chains, pairs, and singles, and possesses flagella, which contributes to its mobility. EuSCAPE_IT042 is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, indicating its adaptation to host-associated habitats. This strain is known to have a significant pathogenicity in humans and is associated with numerous health complications, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. In addition to humans, it can infect a wide range of hosts, including various species of animals and plants, such as Gallus gallus (chickens), Canis lupus familiaris (domestic dogs), and Sus scrofa (pigs). Despite being free-living, Klebsiella pneumoniae demonstrates a strong association with its hosts, leading to severe health consequences such as sepsis and pneumonia. The wide array of potential hosts and the variety of infections it can cause highlight its ecological versatility and adaptability. Understanding the pathogenic mechanisms and interactions of this strain within its host environments is crucial for developing effective treatment and prevention strategies for the infections it causes.