Klebsiella pneumoniae strain EuSCAPE_IT032

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT032 is a gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism and is classified as a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, and singles, which contributes to its overall mobility, aided by the presence of flagella. Its optimal growth temperature is 37°C, and it thrives within a mesophilic temperature range. EuSCAPE_IT032 is notably pathogenic to humans and has been associated with a variety of severe health effects, including bacteremia, pneumonia, urinary tract infections, and intra-abdominal infections, among others. Infections caused by this strain can lead to complications such as sepsis and meningitis, particularly in vulnerable populations. The strain has a biotic relationship that can be described as free-living, and it can inhabit a diverse range of hosts, including Homo sapiens, various species of birds (Gallus gallus, Phasianidae), mammals (Sus scrofa, Canis lupus familiaris, Equidae), and even some aquatic organisms like Danio rerio. This broad host range highlights the ecological versatility of Klebsiella pneumoniae strain EuSCAPE_IT032. Such adaptability may contribute to its pathogenic potential, as it can exploit different environments and hosts, leading to increased transmission and infection rates. Understanding the ecological dynamics and host interactions of this strain is crucial for developing effective public health strategies to mitigate its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT032

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT032
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT032 genome assembly,

Gene Summary

Adenine Count

1217252 bp

Thymine Count

1211534 bp

Guanine Count

1613190 bp

Cytosine Count

1623746 bp

Genome Length

5665722 bp

Protein-coding Genes

5099 genes

Non-Coding Genes

387 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative abc transporter atp-binding protein yrbfSAMEA3538593_00956Not AvailableNegative1004535 - 100534729462.0
inner membrane protein yrbgSAMEA3538593_00957Not AvailablePositive1005557 - 100653434573.8
d-arabinose 5-phosphate isomeraseSAMEA3538593_00958Not AvailablePositive1006549 - 100753535115.8
3-deoxy-d-manno-octulosonate 8-phosphate phosphataseSAMEA3538593_00959Not AvailablePositive1007550 - 100811620402.7
lipopolysaccharide exporter periplasmic proteinSAMEA3538593_00960Not AvailablePositive1008113 - 100868821662.7
lpta, protein essential for lps transport across the periplasmSAMEA3538593_00961Not AvailablePositive1008657 - 100920219863.8
lipopolysaccharide abc transporterSAMEA3538593_00962Not AvailablePositive1009209 - 100993426844.4
rna polymerase sigma-54 factor rponSAMEA3538593_00963Not AvailablePositive1009982 - 101141553927.9
ribosome hibernation protein yhbhSAMEA3538593_00964Not AvailablePositive1011438 - 101172510760.0
pts system transporter subunit iia-like nitrogen-regulatory protein ptsnSAMEA3538593_00965Not AvailablePositive1011796 - 101228417735.3

Displaying genes 1251 – 1260 of 5486 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total