Klebsiella pneumoniae strain EuSCAPE_IT025

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT025 is a notable pathogen classified as a Gram-negative, rod-shaped bacterium. It is capable of forming chains, pairs, or existing as single cells and is characterized by its facultative anaerobic metabolism, allowing it to thrive in varying oxygen conditions. This strain is a chemoheterotroph, relying on organic compounds for energy, and exhibits mobility due to the presence of flagella. EuSCAPE_IT025 is mesophilic, with an optimal growth temperature of 37°C, which aligns with the average human body temperature, indicating its adaptation to host environments. The bacterium has a biotic relationship categorized as free-living, with a wide range of hosts, including Homo sapiens, various domesticated and wild animals, and plants. This strain is associated with numerous health effects in humans, including bacteremia, urinary tract infections, pneumonia, and severe conditions such as sepsis and meningitis. Its pathogenicity highlights its ability to cause significant infections in a variety of hosts, including neonatal sepsis and enteritis in other species. The presence of a single replicon and a double membrane structure is typical of Gram-negative bacteria, further emphasizing its classification. The ecological insight from the data suggests that Klebsiella pneumoniae strain EuSCAPE_IT025 plays a critical role in human health, as well as in animal and environmental interactions, underscoring its potential impact across multiple biological systems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT025

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT025 genome assembly,

Gene Summary

Adenine Count

1224212 bp

Thymine Count

1215966 bp

Guanine Count

1582667 bp

Cytosine Count

1627625 bp

Genome Length

5650470 bp

Protein-coding Genes

5226 genes

Non-Coding Genes

143 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3538586_03433Not AvailableNegative3632534 - 36327979756.89
Dna primaseSAMEA3538586_03434Not AvailableNegative3633134 - 363577694767.5
uncharacterised proteinSAMEA3538586_03435Not AvailableNegative3635766 - 36359787805.4
uncharacterised proteinSAMEA3538586_03436Not AvailableNegative3635975 - 36361697070.63
uncharacterised proteinSAMEA3538586_03437Not AvailableNegative3636162 - 363702231312.3
Hypothetical proteinSAMEA3538586_03438Not AvailableNegative3637015 - 363753919777.3
Antirepressor proteinSAMEA3538586_03439Not AvailableNegative3637705 - 363851130398.5
Transcriptional regulatorSAMEA3538586_03440Not AvailableNegative3638532 - 363881611247.2
uncharacterised proteinSAMEA3538586_03441Not AvailableNegative3639427 - 364007724124.3
IntegraseSAMEA3538586_03442Not AvailableNegative3640077 - 364129746411.3

Displaying genes 61 – 70 of 5369 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total