Klebsiella pneumoniae strain EuSCAPE_DE091

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE091 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. Its typical habitat is host-associated, where it can be found in various organisms, including Homo sapiens, Gallus gallus, and several others across Metazoa and Viridiplantae. This strain exhibits mobility, possessing flagella, and typically arranges itself in chains, pairs, or as singles. EuSCAPE_DE091 thrives optimally at 37°C, classifying it as mesophilic. It has a single replicon and a double membrane structure, which is common among Gram-negative bacteria. As a free-living organism, it is capable of surviving in diverse environments. Klebsiella pneumoniae strain EuSCAPE_DE091 is notable for its pathogenicity in humans, being associated with a wide range of health conditions. These include bacteremia, urinary tract infections, pneumonia, and more severe infections like sepsis and meningitis. The strain is also implicated in infections across different biological hosts, indicating its adaptability and potential risk in both human health and veterinary contexts. The ecological insight from these traits suggests that Klebsiella pneumoniae strain EuSCAPE_DE091 occupies a significant niche in host-associated environments, highlighting its role in both health and disease. Its ability to thrive in various hosts underscores the importance of monitoring this pathogen, particularly in clinical settings where it may contribute to healthcare-associated infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE091

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE091
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE091 genome assembly,

Gene Summary

Adenine Count

1217981 bp

Thymine Count

1210924 bp

Guanine Count

1603807 bp

Cytosine Count

1615052 bp

Genome Length

5647764 bp

Protein-coding Genes

5129 genes

Non-Coding Genes

187 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
carbon-phosphorus lyase complex subunitSAMEA3512119_02830Not AvailablePositive3073749 - 307433320896.4
bacterial phosphonate metabolism protein (phni)SAMEA3512119_02831Not AvailablePositive3074334 - 307539839091.4
phosphonate metabolism protein phnjSAMEA3512119_02832Not AvailablePositive3075391 - 307623932091.4
glutathione import atp-binding protein gsiaSAMEA3512119_02833Not AvailablePositive3076236 - 307699427908.9
lipoprotein-releasing system atp-binding protein loldSAMEA3512119_02834Not AvailablePositive3077102 - 307778224697.9
phosphonate metabolism protein phnmSAMEA3512119_02835Not AvailablePositive3077779 - 307891541961.7
ribose 1,5-bisphosphate phosphokinase phnnSAMEA3512119_02836Not AvailablePositive3078915 - 307947821154.2
carbon-phosphorus lyase complex accessory proteinSAMEA3512119_02837Not AvailablePositive3079494 - 308025227948.6
uncharacterized conserved proteinSAMEA3512119_02838Not AvailableNegative3080274 - 308064214526.5
blue-light-activated proteinSAMEA3512119_02839Not AvailableNegative3080698 - 308298383608.2

Displaying genes 2941 – 2950 of 5316 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total