Klebsiella pneumoniae strain EuSCAPE_DE088

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE088 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain typically resides in host-associated habitats, highlighting its biotic relationships with various hosts, including Homo sapiens, Gallus gallus, and numerous others across different taxa such as Metazoa and Viridiplantae. The strain is capable of mobility, possessing flagella, and can exist in chains, pairs, or as single cells. It thrives optimally at a temperature of 37°C, falling within the mesophilic range. Notably, K. pneumoniae EuSCAPE_DE088 is nonsporulating and has a unique cellular structure characterized by two membranes and a single replicon. Klebsiella pneumoniae is recognized for its pathogenic potential in humans, contributing to a wide spectrum of health issues, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain is implicated in severe conditions such as sepsis, neonatal sepsis, and liver abscesses, demonstrating its significant role in clinical microbiology. Understanding the diverse ecological relationships and pathogenic capabilities of K. pneumoniae strain EuSCAPE_DE088 is crucial for addressing its impact on human health and the broader environment. Its adaptability to various hosts and ability to cause a range of infections underline the importance of ongoing surveillance and research in managing infections associated with this opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE088

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE088
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE088 genome assembly,

Gene Summary

Adenine Count

1154823 bp

Thymine Count

1144424 bp

Guanine Count

1534614 bp

Cytosine Count

1569616 bp

Genome Length

5403477 bp

Protein-coding Genes

4878 genes

Non-Coding Genes

252 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pts system mannose-specific transporter subunits iiabSAMEA3512116_01265Not AvailableNegative1295648 - 129608215625.6
oxygen-insensitive nad(p)h nitroreductaseSAMEA3512116_01266Not AvailableNegative1296330 - 129698323941.3
uncharacterized protein conserved in bacteriaSAMEA3512116_01267Not AvailableNegative1297103 - 129747114282.3
hth-type transcriptional repressor bm3r1SAMEA3512116_01268Not AvailableNegative1297471 - 129805221791.0
metal-dependent hydrolaseSAMEA3512116_01269Not AvailablePositive1298247 - 129934741212.2
regulatory protein soxsSAMEA3512116_01270Not AvailablePositive1299378 - 129971913496.0
protein of uncharacterised function (duf1158)SAMEA3512116_01271Not AvailableNegative1299737 - 12999859487.1
uncharacterised proteinSAMEA3512116_01272Not AvailableNegative1300175 - 13002853997.1
probable cation-transporting atpase fSAMEA3512116_01273Not AvailablePositive1300488 - 130321198564.1
multidrug resistance protein mdte precursorSAMEA3512116_01274Not AvailablePositive1303264 - 130434338726.3

Displaying genes 1461 – 1470 of 5130 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total