Klebsiella pneumoniae strain EuSCAPE_DE086

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE086 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophy as its energy source. This strain is characterized by its ability to form chains, pairs, and singles and is motile, equipped with flagella. It thrives optimally at 37°C, placing it within the mesophilic temperature range. EuSCAPE_DE086 is associated with a broad spectrum of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae, indicating its adaptability to diverse biological environments. Its pathogenic potential is significant, as it is linked to numerous health conditions in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is also associated with infections in other species, such as mink pneumonia and early onset neonatal sepsis. With one replicon and two membranes, this strain does not form spores, which is typical of many pathogenic bacteria. Its free-living biotic relationship suggests it can survive independently in various environments, which may facilitate its transmission and persistence in host populations. Understanding the ecological and biological dynamics of Klebsiella pneumoniae strain EuSCAPE_DE086 is crucial, particularly in relation to its pathogenicity and the impacts on both human and animal health. Its wide host range and association with severe infections highlight the importance of monitoring and controlling its spread in clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE086

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE086
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE086 genome assembly,

Gene Summary

Adenine Count

1178645 bp

Thymine Count

1173744 bp

Guanine Count

1572424 bp

Cytosine Count

1575194 bp

Genome Length

5500007 bp

Protein-coding Genes

4992 genes

Non-Coding Genes

168 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
serine/threonine protein kinaseSAMEA3512114_04427Not AvailablePositive4752616 - 475360238330.6
thiol:disulfide interchange protein dsba precursorSAMEA3512114_04428Not AvailablePositive4753630 - 475425322946.6
probable acyltransferase yihgSAMEA3512114_04429Not AvailableNegative4754302 - 475520134938.2
dna polymerase iSAMEA3512114_04430Not AvailablePositive4755598 - 4758390103247.0
probable gtp-binding protein engbSAMEA3512114_04431Not AvailableNegative4758738 - 475937023533.3
der gtpase-activating protein yihiSAMEA3512114_04432Not AvailablePositive4759954 - 476046018780.9
oxygen-independent coproporphyrinogen-iii oxidaseSAMEA3512114_04433Not AvailablePositive4760649 - 476202252182.3
nitrogen assimilation regulatory proteinSAMEA3512114_04434Not AvailableNegative4762279 - 476368852338.8
nitrogen regulation protein nr(ii)SAMEA3512114_04435Not AvailableNegative4763697 - 476474638428.5
glutamine synthetaseSAMEA3512114_04436Not AvailableNegative4764935 - 476634451855.7

Displaying genes 4461 – 4470 of 5160 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total