Klebsiella pneumoniae strain EuSCAPE_DE009

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE009 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, primarily functioning as a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, or exist as single cells, and it possesses flagella, contributing to its mobility. Its optimal growth temperature is 37°C, classifying it as mesophilic. K. pneumoniae EuSCAPE_DE009 is associated with various hosts, including Homo sapiens, Gallus gallus, and several other Metazoa and Viridiplantae species. This broad host range indicates its ecological versatility and potential for cross-species transmission. The bacterium is free-living in its habitat, but it is notably pathogenic to humans, causing a range of serious health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain does not form spores and contains a single replicon with a double membrane structure. Its pathogenicity is significant, with implications for human health, particularly in hospital settings where infections can lead to severe outcomes. Given its capability to cause various infections, including neonatal sepsis and pyogenic liver abscesses, understanding K. pneumoniae EuSCAPE_DE009 is crucial for developing strategies to manage and prevent infections it may cause. The presence of K. pneumoniae in diverse environments alongside its pathogenic potential highlights the importance of monitoring this organism in both clinical and ecological contexts, particularly as it relates to human health and antibiotic resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE009

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE009
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE009 genome assembly,

Gene Summary

Adenine Count

1114731 bp

Thymine Count

1116284 bp

Guanine Count

1506163 bp

Cytosine Count

1506618 bp

Genome Length

5243796 bp

Protein-coding Genes

4799 genes

Non-Coding Genes

130 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribitol 2-dehydrogenaseSAMEA3512036_00026Not AvailableNegative28211 - 2896026519.3
ribitol operon repressorSAMEA3512036_00027Not AvailablePositive29215 - 3021636561.0
putative sorc-family transcriptional regulatorSAMEA3512036_00028Not AvailableNegative30239 - 3118035005.0
d-arabinitol dehydrogenaseSAMEA3512036_00029Not AvailablePositive31387 - 3275451026.8
xylulose kinaseSAMEA3512036_00030Not AvailablePositive32764 - 3422752773.3
ribitol/xylitol/arabitol transporterSAMEA3512036_00031Not AvailablePositive34298 - 3557546815.1
had hydrolase family iaSAMEA3512036_00032Not AvailablePositive35624 - 3628624044.7
putative mandelate racemase / muconate lactonizing enzymeSAMEA3512036_00033Not AvailablePositive36584 - 3773842508.6
putative dipeptide abc transport system periplasmic binding componentSAMEA3512036_00034Not AvailablePositive37858 - 3948060166.4
dipeptide transport system permease dppbSAMEA3512036_00035Not AvailablePositive39477 - 4051437473.8

Displaying genes 81 – 90 of 4929 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total