Klebsiella pneumoniae strain EuSCAPE_DE080

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE080 is a gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain is notable for its ability to thrive in host-associated environments, primarily affecting a variety of hosts including Homo sapiens, Gallus gallus, and other metazoans. It exhibits mobility due to the presence of flagella and typically arranges itself in chains, pairs, or as singles. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, further indicating its pathogenic potential in human hosts. K. pneumoniae is implicated in a wide range of health issues, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The bacterium can also cause infections in other species, including domestic animals and plants, emphasizing its versatility in different environments. The strain EuSCAPE_DE080 has a single replicon and two membranes, which is characteristic of gram-negative bacteria. Its nonsporulating nature suggests that it relies on other survival strategies in hostile environments. The diverse pathogenicity observed in this strain highlights its significance as a public health concern, particularly in nosocomial infections. Understanding K. pneumoniae strain EuSCAPE_DE080's ecological relationships and pathogenicity is crucial for developing effective treatment strategies and managing the health risks associated with infections in both humans and animals.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE080

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE080
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE080 genome assembly,

Gene Summary

Adenine Count

1124327 bp

Thymine Count

1124187 bp

Guanine Count

1506107 bp

Cytosine Count

1511489 bp

Genome Length

5266110 bp

Protein-coding Genes

4831 genes

Non-Coding Genes

145 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3512108_00525Not AvailablePositive546227 - 5464518228.06
uncharacterised proteinSAMEA3512108_00526Not AvailablePositive546448 - 54679213540.6
Hypothetical proteinSAMEA3512108_00527Not AvailablePositive546785 - 54750726952.5
uncharacterised proteinSAMEA3512108_00528Not AvailablePositive547504 - 54792916765.8
Hypothetical proteinSAMEA3512108_00529Not AvailablePositive548049 - 5483129697.87
AttrNot AvailableNot AvailablePositive554561 - 554575Not Available
Gp58SAMEA3512108_03946Not AvailablePositive4216321 - 421722034303.5
membrane protein ycjfSAMEA3512108_03947Not AvailableNegative4217310 - 421837139122.4
putative enzymeSAMEA3512108_03948Not AvailableNegative4218368 - 421976552764.8
phage shock protein dSAMEA3512108_03949Not AvailableNegative4219868 - 42200867807.01

Displaying genes 51 – 60 of 4976 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total