Klebsiella pneumoniae strain EuSCAPE_DE075

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE075 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and possesses flagella, contributing to its mobility. It thrives optimally at 37°C and falls within the mesophilic temperature range. This bacterium is primarily associated with human hosts (Homo sapiens) but has also been identified in a range of other organisms, including Gallus gallus, various Metazoa, and several species within the animal kingdom such as Canis lupus familiaris and Sus scrofa. The diverse host range indicates its ecological versatility and potential for transmission across species. Klebsiella pneumoniae EuSCAPE_DE075 is known for its pathogenicity in humans, being implicated in various health conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to cause severe infections underlines its importance in clinical settings, particularly in immunocompromised individuals. As a non-sporulating, free-living organism with a single replicon and a dual-membrane structure, this strain exemplifies the complex interactions between human health and microbial life. The significant health impacts associated with Klebsiella pneumoniae reinforce the need for continued surveillance and research into its behavior, resistance mechanisms, and ecological roles, especially given the rise of antibiotic resistance in pathogenic strains.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE075

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE075
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE075 genome assembly,

Gene Summary

Adenine Count

1204800 bp

Thymine Count

1210981 bp

Guanine Count

1609125 bp

Cytosine Count

1591840 bp

Genome Length

5616746 bp

Protein-coding Genes

5125 genes

Non-Coding Genes

227 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttrNot AvailableNot AvailablePositive2903246 - 2903260Not Available
Major head subunitSAMEA3512103_02762Not AvailableNegative2912695 - 291391243776.4
AttlNot AvailableNot AvailablePositive2913823 - 2913835Not Available
Head maturation proteaseSAMEA3512103_02763Not AvailableNegative2913922 - 291477029506.1
Portal proteinSAMEA3512103_02764Not AvailableNegative2914784 - 291609148695.1
Terminase large subunit-like proteinSAMEA3512103_02765Not AvailableNegative2916091 - 291783364839.8
Terminase small subunitSAMEA3512103_02766Not AvailableNegative2917787 - 291825116943.5
Hnh endonucleaseSAMEA3512103_02767Not AvailableNegative2918434 - 291877513085.8
Hypothetical proteinSAMEA3512103_02768Not AvailableNegative2918877 - 291931716616.9
Hypothetical proteinSAMEA3512103_02769Not AvailableNegative2919708 - 29199539005.58

Displaying genes 81 – 90 of 5352 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total