Klebsiella pneumoniae strain EuSCAPE_DE035

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE035 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and ability to thrive at an optimal temperature of 37°C, classifying it as mesophilic. This strain exhibits mobility due to the presence of flagella and can be found in various cell arrangements, including chains, pairs, and singles. It possesses a single replicon and is surrounded by two membranes, typical of Gram-negative bacteria. As a chemoheterotroph, K. pneumoniae strain EuSCAPE_DE035 derives its energy from organic compounds, allowing it to inhabit diverse environments, particularly those associated with hosts. It has been identified in a broad range of hosts, including Homo sapiens and various animals such as Gallus gallus, Sus scrofa, and Canis lupus familiaris. This bacterium is known for its pathogenic effects in humans, being associated with conditions like bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Notably, K. pneumoniae strains, including EuSCAPE_DE035, have significant implications for public health due to their potential to cause severe infections. The presence of this strain in various animal hosts may suggest a complex ecological role, potentially facilitating the transmission of antibiotic resistance genes among different species. This underscores the importance of monitoring such bacteria in both clinical and environmental settings to better understand their impact on human health and the ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE035

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE035
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE035 genome assembly,

Gene Summary

Adenine Count

1099911 bp

Thymine Count

1093350 bp

Guanine Count

1482404 bp

Cytosine Count

1498290 bp

Genome Length

5173955 bp

Protein-coding Genes

4682 genes

Non-Coding Genes

297 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Baseplate assembly proteinSAMEA3512062_00385Not AvailableNegative399100 - 39968720629.4
Virion morphogenesis proteinSAMEA3512062_00386Not AvailableNegative399684 - 40031923864.7
Tail proteinSAMEA3512062_00387Not AvailableNegative400316 - 40078317570.1
PeptidaseSAMEA3512062_00388Not AvailableNegative400784 - 40111912156.8
LysozymeSAMEA3512062_00389Not AvailableNegative401306 - 40185120101.1
Tail proteinSAMEA3512062_00390Not AvailableNegative401848 - 40212610353.6
Tail proteinSAMEA3512062_00391Not AvailableNegative402123 - 4023237485.96
Head completion-stabilization proteinSAMEA3512062_00392Not AvailableNegative402323 - 40283819135.5
Small terminase subunitSAMEA3512062_00393Not AvailableNegative402951 - 40380831020.8
Major capsid proteinSAMEA3512062_00394Not AvailableNegative403858 - 40489238408.4

Displaying genes 71 – 80 of 4979 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total