Klebsiella pneumoniae strain EuSCAPE_DE067

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE067 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain typically thrives in host-associated environments, with an optimal growth temperature of 37°C, classifying it as mesophilic. K. pneumoniae EuSCAPE_DE067 exhibits mobility due to the presence of flagella and can be found in various arrangements, including chains, pairs, and singles. This strain is significant in clinical microbiology due to its association with numerous health effects in humans and other hosts, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. In addition to humans (Homo sapiens), it has been identified in a wide range of hosts, including domesticated animals such as Gallus gallus (chickens) and Sus scrofa (pigs), as well as other Metazoa and Viridiplantae. K. pneumoniae strain EuSCAPE_DE067 is nonsporulating and has a complex biotic relationship, functioning as a free-living organism. Its pathogenicity is particularly concerning in healthcare settings, where it can lead to severe conditions such as sepsis and pneumonia. The strain's ability to cause infections across various species highlights its ecological adaptability and potential as an opportunistic pathogen. Overall, the diverse array of hosts and health implications associated with K. pneumoniae strain EuSCAPE_DE067 underscores the importance of understanding its biology and ecology in both clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE067

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE067
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE067 genome assembly,

Gene Summary

Adenine Count

1205484 bp

Thymine Count

1208051 bp

Guanine Count

1611089 bp

Cytosine Count

1611714 bp

Genome Length

5636338 bp

Protein-coding Genes

5108 genes

Non-Coding Genes

338 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3512094_00905Not AvailablePositive949812 - 9500037326.97
Terminase small subunitSAMEA3512094_00906Not AvailablePositive949961 - 95031713284.7
Terminase large subunitSAMEA3512094_00907Not AvailablePositive950301 - 95196262400.3
uncharacterised proteinSAMEA3512094_00908Not AvailablePositive951965 - 9521567533.4
dna-binding protein fisSAMEA3512094_00909Not AvailableNegative952310 - 95260611240.6
trna dihydrouridine synthase bSAMEA3512094_00910Not AvailableNegative952631 - 95359635837.2
50s ribosomal protein l11 methyltransferaseSAMEA3512094_00911Not AvailableNegative953954 - 95483531873.9
Hypothetical proteinSAMEA3512094_00912Not AvailableNegative954847 - 95629851694.2
AttrNot AvailableNot AvailablePositive961022 - 961033Not Available
Lysr family transcriptional regulatorSAMEA3512094_01592Not AvailablePositive1648548 - 164943233132.1

Displaying genes 21 – 30 of 5446 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total