Klebsiella pneumoniae strain EuSCAPE_DE041

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE041 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is classified as a chemoheterotroph, deriving its energy from organic compounds. It typically exists in chains, pairs, or as single cells and possesses flagella, indicating mobility. This bacterium is mesophilic, with an optimal growth temperature of 37°C, which aligns with the average human body temperature, suggesting an adaptation for survival in host organisms. EuSCAPE_DE041 has a unique habitat, being host-associated and demonstrating a free-living biotic relationship. It has been identified in a wide array of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoan, plant, and animal species. Klebsiella pneumoniae strain EuSCAPE_DE041 is known for its pathogenicity in humans, associated with a spectrum of serious health conditions. These include bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's ability to cause a range of infections highlights its potential impact on public health, particularly in vulnerable populations. The presence of this strain in multiple hosts, including mammals and birds, underscores its ecological versatility and potential for cross-species transmission. This adaptability may facilitate its persistence in various environments, raising considerations for infection control and prevention strategies in both clinical and agricultural settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE041

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE041
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE041 genome assembly,

Gene Summary

Adenine Count

1152850 bp

Thymine Count

1142173 bp

Guanine Count

1551937 bp

Cytosine Count

1535150 bp

Genome Length

5382110 bp

Protein-coding Genes

4854 genes

Non-Coding Genes

272 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Threonyl-trna synthetaseSAMEA3512068_00314Not AvailablePositive306899 - 30882773941.2
Translation initiation factor 3SAMEA3512068_00315Not AvailablePositive308939 - 30937316595.4
AttlNot AvailableNot AvailablePositive3815451 - 3815505Not Available
IntegraseSAMEA3512068_03612Not AvailableNegative3815545 - 381663040784.4
Repressor ciSAMEA3512068_03613Not AvailableNegative3816634 - 381725423098.5
Regulatory proteinSAMEA3512068_03614Not AvailablePositive3817355 - 38175918927.07
Regulatory protein ciiSAMEA3512068_03615Not AvailablePositive3817626 - 381813518296.1
Hypothetical proteinSAMEA3512068_03616Not AvailablePositive3818307 - 381864512770.5
Hypothetical proteinSAMEA3512068_03617Not AvailablePositive3818713 - 38189468605.2
Trar/dksa family transcriptional regulatorSAMEA3512068_03618Not AvailablePositive3818946 - 38191738282.04

Displaying genes 81 – 90 of 5126 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total