Klebsiella pneumoniae strain EuSCAPE_DE027

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE027 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain is capable of existing in diverse habitats, primarily associated with various hosts, including Homo sapiens, Gallus gallus, and other metazoans, as well as Viridiplantae and aquatic species like Danio rerio. Its cell arrangement can be observed in chains, pairs, and singles, and it possesses flagella, allowing for mobility. The optimal growth temperature for K. pneumoniae EuSCAPE_DE027 is approximately 37°C, placing it within the mesophilic temperature range. This bacterium has a single replicon and a double membrane structure, which is characteristic of Gram-negative bacteria. K. pneumoniae strain EuSCAPE_DE027 is known for its pathogenicity in humans and can cause a variety of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Other notable health effects include neonatal sepsis, liver abscesses, endophthalmitis, and septicemia. The bacterium is also implicated in infections in other animals, demonstrating its ecological versatility and potential as a zoonotic pathogen. In conclusion, K. pneumoniae EuSCAPE_DE027 exemplifies the complex interplay between human health and microbial ecology. Its ability to thrive in diverse host environments and cause a range of infections underscores the importance of understanding its biology and pathogenic mechanisms in the context of public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE027

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE027
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE027 genome assembly,

Gene Summary

Adenine Count

1159783 bp

Thymine Count

1160758 bp

Guanine Count

1558327 bp

Cytosine Count

1539461 bp

Genome Length

5418329 bp

Protein-coding Genes

4973 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna-damage-inducible protein iSAMEA3512054_00055Not AvailablePositive56109 - 563609293.82
biofilm formation regulatory protein bsssSAMEA3512054_00056Not AvailablePositive56663 - 569179737.27
n-methyl-l-tryptophan oxidaseSAMEA3512054_00057Not AvailablePositive57043 - 5816140366.5
protein of uncharacterised function (duf2770)SAMEA3512054_00058Not AvailablePositive58233 - 583464712.08
putative rhodanese-related sulfurtransferaseSAMEA3512054_00059Not AvailableNegative58332 - 5939640237.0
lipid a biosynthesis (kdo) 2-(lauroyl)-lipid iva acyltransferaseSAMEA3512054_00060Not AvailablePositive59602 - 6052235542.0
multidrug-efflux transporter, major facilitator superfamily (mfs)SAMEA3512054_00061Not AvailablePositive60694 - 6192043594.6
acidic protein msybSAMEA3512054_00062Not AvailablePositive62012 - 6239814763.3
outer membrane lipoproteinSAMEA3512054_00063Not AvailableNegative62399 - 626268316.15
glucans biosynthesis glucosyltransferase hSAMEA3512054_00064Not AvailableNegative62693 - 6522196026.5

Displaying genes 101 – 110 of 5080 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total