Klebsiella pneumoniae strain 3754STDY6170042

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 3754STDY6170042 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. It typically arranges itself in chains, pairs, or singles and possesses flagella, allowing for mobility. This strain has one replicon and is characterized by a double membrane structure. It thrives optimally at 37°C and fits within a mesophilic temperature range. This strain is predominantly found in association with various hosts, including Homo sapiens, Gallus gallus, and other vertebrates such as Canis lupus familiaris and Sus scrofa. It has a free-living biotic relationship, indicating its ability to exist independently in different environments. However, it is also recognized for its pathogenicity in humans, being responsible for a range of serious health effects, such as bacteremia, urinary tract infections, pneumonia, and sepsis. The diverse host range suggests that Klebsiella pneumoniae strain 3754STDY6170042 is well-adapted to various ecological niches, potentially contributing to its pathogenicity in humans and other species. Its ability to thrive in different environments and cause significant health issues underscores the importance of monitoring and understanding this bacterium in clinical and ecological contexts. This adaptability highlights the challenges of managing infections caused by Klebsiella pneumoniae in a variety of hosts, including humans and livestock, emphasizing the necessity for ongoing research and surveillance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 3754STDY6170042

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 3754STDY6170042
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 3754STDY6170042 genome assembly,

Gene Summary

Adenine Count

1246927 bp

Thymine Count

1248455 bp

Guanine Count

1636424 bp

Cytosine Count

1638163 bp

Genome Length

5769969 bp

Protein-coding Genes

5092 genes

Non-Coding Genes

392 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Major capsid proteinSAMEA3512051_01331Not AvailableNegative1385923 - 138698139803.3
Capsid scaffolding proteinSAMEA3512051_01332Not AvailableNegative1387055 - 138790931247.8
TerminaseSAMEA3512051_01333Not AvailablePositive1388075 - 138984466590.6
Portal proteinSAMEA3512051_01334Not AvailablePositive1389844 - 139088739362.9
Hypothetical proteinSAMEA3512051_01335Not AvailableNegative1391282 - 13913833706.69
Hypothetical proteinSAMEA3512051_01336Not AvailableNegative1391400 - 13915947418.79
uncharacterised proteinSAMEA3512051_01337Not AvailableNegative1391734 - 139209313807.8
Rna-directed dna polymeraseSAMEA3512051_01338Not AvailableNegative1392163 - 139311336238.7
Hypothetical proteinSAMEA3512051_01339Not AvailableNegative1393436 - 13935916049.12
TumSAMEA3512051_01340Not AvailableNegative1394020 - 139446016639.0

Displaying genes 81 – 90 of 5484 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total