Klebsiella pneumoniae strain EuSCAPE_IL017

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL017 is a Gram-negative, rod-shaped bacterium with a facultative anaerobic metabolism, relying on chemoheterotrophic energy sources. It typically exists in host-associated environments, exhibiting mobility due to the presence of flagella. This strain can be found in various arrangements, including chains, pairs, and singles, and it thrives optimally at 37°C, placing it within a mesophilic temperature range. As a free-living organism, Klebsiella pneumoniae has a broad host range, infecting Homo sapiens, various vertebrates, and plants, including Gallus gallus, Danio rerio, and Sus scrofa. It is associated with numerous health conditions, predominantly affecting humans, where it can cause severe infections such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is notably pathogenic to humans, highlighting its potential impact on public health. Klebsiella pneumoniae EuSCAPE_IL017 does not undergo sporulation and possesses a single replicon and a double-membrane structure. The extensive list of health effects associated with this strain underscores its clinical significance, particularly its role in various forms of infection that can lead to serious health complications. The ecological insight derived from its diverse host range and significant pathogenicity reflects the adaptability and resilience of Klebsiella pneumoniae, demonstrating its ability to thrive in multiple environments and interact with various biological systems. This adaptability may contribute to its persistence in healthcare settings and its relevance in the study of antibiotic resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL017

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL017
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL017 genome assembly,

Gene Summary

Adenine Count

1122342 bp

Thymine Count

1124387 bp

Guanine Count

1528295 bp

Cytosine Count

1506491 bp

Genome Length

5281515 bp

Protein-coding Genes

4735 genes

Non-Coding Genes

246 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
IntegraseSAMEA3538475_03651Not AvailablePositive3887983 - 388906840784.4
AttrNot AvailableNot AvailablePositive3893366 - 3893378Not Available
AttlNot AvailableNot AvailablePositive4310938 - 4310952Not Available
Gp245SAMEA3538475_04068Not AvailableNegative4316017 - 431682630480.2
Abc transporterSAMEA3538475_04069Not AvailableNegative4316828 - 431782037597.8
peptide transport system permease protein sapcSAMEA3538475_04070Not AvailableNegative4317820 - 431871031661.4
IntegraseSAMEA3538475_04071Not AvailablePositive4318887 - 432007445840.6
Hypothetical proteinSAMEA3538475_04072Not AvailableNegative4320542 - 432085011232.6
Hypothetical proteinSAMEA3538475_04073Not AvailableNegative4320847 - 432148824779.7
Conserved hypothetical bacteriophage proteinSAMEA3538475_04074Not AvailableNegative4321547 - 432265640755.1

Displaying genes 51 – 60 of 4981 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total