Klebsiella pneumoniae strain EuSCAPE_DE017

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE017 is a Gram-negative bacterium characterized by its rod shape and the presence of flagella, which allows for mobility. This strain is classified as a facultative anaerobe, enabling it to thrive in both aerobic and anaerobic environments. It typically exists in chains, pairs, or singles and is chemoheterotrophic, relying on organic compounds for energy. The optimal temperature for growth is 37°C, placing it within the mesophilic range. This strain is notably significant in human health, as it is associated with a variety of serious infections, including bacteremia, urinary tract infections, pneumonia, and liver abscesses. Other health effects include meningitis, wound infections, and various forms of sepsis, highlighting its pathogenic potential. The bacterium has been identified in multiple hosts, including Homo sapiens, domestic animals like Gallus gallus (chickens) and Sus scrofa (pigs), as well as other vertebrates, indicating a broad ecological niche. With a single replicon and a double membrane structure, Klebsiella pneumoniae strain EuSCAPE_DE017 demonstrates characteristics typical of many pathogenic bacteria. Its ability to cause a wide range of infections in various hosts underscores its adaptability and the importance of monitoring its spread in both human and veterinary contexts. The presence of this strain in diverse environments suggests that it plays a significant role in microbial ecosystems, potentially influencing health across multiple species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE017

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE017
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE017 genome assembly,

Gene Summary

Adenine Count

1202386 bp

Thymine Count

1202137 bp

Guanine Count

1602067 bp

Cytosine Count

1589840 bp

Genome Length

5596430 bp

Protein-coding Genes

5197 genes

Non-Coding Genes

89 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
udp-3-o-[3-hydroxymyristoyl] n-acetylglucosamine deacetylaseSAMEA3512044_01438Not AvailableNegative1581365 - 158228234048.0
cell division protein ftszSAMEA3512044_01439Not AvailableNegative1582383 - 158353440344.4
cell division protein ftsaSAMEA3512044_01440Not AvailableNegative1583597 - 158485945316.7
cell division protein ftsqSAMEA3512044_01441Not AvailableNegative1584856 - 158568631302.4
d-alanine--d-alanine ligaseSAMEA3512044_01442Not AvailableNegative1585688 - 158660832703.2
udp-n-acetylmuramate-alanine ligaseSAMEA3512044_01443Not AvailableNegative1586601 - 158807653478.9
udp-n-acetylglucosamine-n-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol n-acetylglucosamine transferaseSAMEA3512044_01444Not AvailableNegative1588124 - 158917037116.1
cell division protein ftswSAMEA3512044_01445Not AvailableNegative1589191 - 159046547211.6
udp-n-acetylmuramoylalanine--d-glutamate ligaseSAMEA3512044_01446Not AvailableNegative1590465 - 159178146879.6
phospho-n-acetylmuramoyl-pentapeptide- transferaseSAMEA3512044_01447Not AvailableNegative1591784 - 159286639940.2

Displaying genes 1491 – 1500 of 5286 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total