Klebsiella pneumoniae strain EuSCAPE_IL012

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL012 is a gram-negative, rod-shaped bacterium that exhibits a variety of pathogenic behaviors in humans and other hosts. As a facultative anaerobe and chemoheterotroph, it thrives optimally at 37°C, within a mesophilic temperature range. This strain is characterized by its ability to form chains, pairs, and singles, and it possesses flagella, indicating its mobility. The bacterium has a biotic relationship that is free-living, yet it is associated with numerous hosts, including Homo sapiens, Gallus gallus, and various other animals and plants. This broad host range suggests a versatile ecological niche, allowing for significant interaction with diverse biological systems. K. pneumoniae strain EuSCAPE_IL012 is known for its pathogenicity in humans, being implicated in a wide array of health issues, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. These infections can be particularly severe, leading to complications such as liver abscesses and meningitis. The presence of a single replicon and two membranes aligns with the typical structure of gram-negative bacteria, which contributes to their resilience in various environments. The strain's pathogenic potential, particularly in human health, highlights the importance of understanding its ecological interactions and transmission dynamics. Given the strain's association with both free-living conditions and opportunistic infections, it underscores the need for continued research on its epidemiology and control measures in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL012

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL012
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL012 genome assembly,

Gene Summary

Adenine Count

1170310 bp

Thymine Count

1169205 bp

Guanine Count

1576426 bp

Cytosine Count

1565969 bp

Genome Length

5481910 bp

Protein-coding Genes

4876 genes

Non-Coding Genes

413 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
anaerobic glycerol-3-phosphate dehydrogenase subunit aSAMEA3538470_00176Not AvailablePositive221493 - 22311559155.0
anaerobic glycerol-3-phosphate dehydrogenase subunit bSAMEA3538470_00177Not AvailablePositive223105 - 22436445166.6
anaerobic glycerol-3-phosphate dehydrogenase subunit cSAMEA3538470_00178Not AvailablePositive224361 - 22553943860.2
2-keto-3-deoxy-l-rhamnonate aldolaseSAMEA3538470_00179Not AvailableNegative225561 - 22636428874.5
transporter, major facilitator family proteinSAMEA3538470_00180Not AvailableNegative226379 - 22767146086.2
putative dehydrataseSAMEA3538470_00181Not AvailableNegative227711 - 2279147673.27
putative dehydrataseSAMEA3538470_00182Not AvailableNegative227911 - 22891536624.1
transcriptional regulator yfax, hth-typeSAMEA3538470_00183Not AvailableNegative228926 - 22971128865.9
competence/damage-inducible protein cinaSAMEA3538470_00184Not AvailableNegative229916 - 23111243458.5
outer membrane protein, yfazSAMEA3538470_00185Not AvailableNegative231215 - 23175718647.8

Displaying genes 561 – 570 of 5289 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total