Klebsiella pneumoniae strain EuSCAPE_IL009

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL009 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain is classified as a chemoheterotroph, deriving its energy from organic compounds, and is typically found in host-associated environments. It exhibits a mesophilic temperature range, with optimal growth occurring at 37°C. The bacterium is capable of existing in various cell arrangements, including chains, pairs, and singles. It possesses a single replicon and is surrounded by two membranes. As a free-living organism, Klebsiella pneumoniae strain EuSCAPE_IL009 is known to infect a wide range of hosts, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus) and pigs (Sus scrofa), as well as other metazoans and plants. This strain is notably pathogenic to humans, being associated with a variety of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. Its presence can lead to severe infections such as liver abscesses, meningitis, and pulmonary infections, highlighting its clinical significance. The ecological insight gained from studying Klebsiella pneumoniae strain EuSCAPE_IL009 underscores the importance of understanding host interactions and the potential for this bacterium to cause widespread illness across a diverse array of hosts. This trait reinforces the need for vigilance in monitoring and managing infections caused by this opportunistic pathogen in both human and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL009

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL009
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL009 genome assembly,

Gene Summary

Adenine Count

1184053 bp

Thymine Count

1186143 bp

Guanine Count

1584852 bp

Cytosine Count

1588860 bp

Genome Length

5543908 bp

Protein-coding Genes

4993 genes

Non-Coding Genes

364 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane protein x precursorSAMEA3538467_01650Not AvailablePositive1724572 - 172508418464.4
putative phosphoethanolamine transferase ybipSAMEA3538467_01651Not AvailableNegative1725175 - 172675559550.1
uncharacterised proteinSAMEA3538467_01652Not AvailableNegative1727023 - 17271484724.98
manganese transport regulatorSAMEA3538467_01653Not AvailablePositive1727334 - 172780717816.4
inner membrane protein ybirSAMEA3538467_01654Not AvailablePositive1727804 - 172891640842.8
aryl-phospho-beta-d-glucosidase bglaSAMEA3538467_01655Not AvailablePositive1729086 - 173046253159.2
glucomannan utilization protein rSAMEA3538467_01656Not AvailablePositive1730531 - 173124726956.5
probable l,d-transpeptidase ybis precursorSAMEA3538467_01657Not AvailableNegative1731393 - 173238235652.0
protein tyrosine/serine phosphataseSAMEA3538467_01658Not AvailableNegative1732508 - 173329328513.2
uncharacterized abc transporter atp-binding protein yhesSAMEA3538467_01659Not AvailablePositive1733472 - 173506459687.1

Displaying genes 1891 – 1900 of 5357 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total