Klebsiella pneumoniae strain EuSCAPE_LT007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_LT007 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. It typically arranges itself in chains, pairs, or as single cells, demonstrating mobility through the presence of flagella. The strain thrives optimally at 37°C and falls within the mesophilic temperature range. This bacterium is primarily associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other vertebrates and invertebrates. It has been implicated in a wide array of health issues, including bacteremia, urinary tract infections, pneumonia, and several other serious infections such as meningitis and sepsis. The strain is notably pathogenic to humans, contributing to significant clinical outcomes, especially in immunocompromised individuals. Klebsiella pneumoniae strain EuSCAPE_LT007 is characterized by a free-living biotic relationship, yet it has a profound impact on host health, particularly in the context of opportunistic infections. Its ability to cause infections across a diverse range of hosts highlights its ecological versatility and adaptability. The strain's presence in various environments suggests a complex interplay between pathogenicity and its ecological roles, indicating potential reservoirs of infection that may influence public health strategies. Understanding the interactions of this strain within its habitats can provide insights into infection control and the management of Klebsiella-associated diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_LT007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_LT007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_LT007 genome assembly,

Gene Summary

Adenine Count

1151649 bp

Thymine Count

1154300 bp

Guanine Count

1552142 bp

Cytosine Count

1547208 bp

Genome Length

5405299 bp

Protein-coding Genes

4871 genes

Non-Coding Genes

301 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Amber mutation-suppressing proteinSAMEA3538454_02666Not AvailableNegative2778299 - 277886521200.0
Dna-binding transcriptional regulatorSAMEA3538454_02667Not AvailableNegative2778883 - 27791289188.91
Head size determination protein sidSAMEA3538454_02668Not AvailableNegative2779125 - 277986227210.3
Transcriptional regulatorSAMEA3538454_02669Not AvailablePositive2780423 - 27806899737.63
Putative ci repressorSAMEA3538454_02670Not AvailablePositive2781040 - 27812347109.72
uncharacterised proteinSAMEA3538454_02671Not AvailablePositive2781231 - 27814588577.31
Hypothetical proteinSAMEA3538454_02672Not AvailablePositive2781455 - 278177511761.5
Dna primaseSAMEA3538454_02673Not AvailablePositive2781790 - 278412384560.3
AttrNot AvailableNot AvailablePositive2784665 - 2784678Not Available
TransposaseSAMEA3538454_02674Not AvailablePositive2784869 - 278513510280.5

Displaying genes 81 – 90 of 5172 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total