Klebsiella pneumoniae strain EuSCAPE_DE013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DE013 is a Gram-negative, rod-shaped bacterium known for its pathogenicity, particularly in human hosts. This strain is facultatively anaerobic and utilizes a chemoheterotrophic energy source, allowing it to thrive in various environments, including host-associated habitats. It typically forms chains, pairs, or singles and possesses flagella, indicating mobility. EuSCAPE_DE013 is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, facilitating its role as a human pathogen. This strain is capable of causing a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Other notable infections attributed to this strain include liver abscesses, meningitis, and sepsis, highlighting its significant impact on human health. In addition to its human pathogenicity, K. pneumoniae strain EuSCAPE_DE013 has been associated with a variety of hosts, including domestic animals such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as other metazoans and plants. This broad host range suggests potential ecological interactions and the ability of the bacterium to adapt to diverse environments. Overall, the pathogenicity of K. pneumoniae strain EuSCAPE_DE013 and its presence in both human and animal hosts underscore the importance of monitoring this bacterium in clinical and ecological contexts to mitigate its impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DE013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DE013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DE013 genome assembly,

Gene Summary

Adenine Count

1208109 bp

Thymine Count

1206913 bp

Guanine Count

1617181 bp

Cytosine Count

1596234 bp

Genome Length

5628437 bp

Protein-coding Genes

5028 genes

Non-Coding Genes

388 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3512040_01396Not AvailablePositive1421717 - 142220217847.6
Tail proteinSAMEA3512040_01397Not AvailablePositive1422199 - 142329640616.3
Hypothetical proteinSAMEA3512040_01398Not AvailableNegative1423608 - 142398513991.1
AttrNot AvailableNot AvailablePositive1424080 - 1424126Not Available
Tmrna,resume;Not AvailableNot AvailablePositive1424082 - 1424444Not Available
Ssra-binding proteinSAMEA3512040_01400Not AvailableNegative1424588 - 142507018240.1
Type ii toxin-antitoxin system toxin rataSAMEA3512040_01401Not AvailablePositive1425220 - 142565716023.5
Rnfh family proteinSAMEA3512040_01402Not AvailablePositive1425647 - 142593710835.1
Outer membrane protein assembly factor bameSAMEA3512040_01403Not AvailableNegative1426004 - 142634512414.0
Dna repair protein recnSAMEA3512040_01404Not AvailableNegative1426493 - 142815461364.2

Displaying genes 111 – 120 of 5416 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total