Klebsiella pneumoniae strain EuSCAPE_EE009

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_EE009 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and can be found in various cell arrangements, including chains, pairs, and singles. This strain is chemoheterotrophic, deriving its energy from organic compounds, and exhibits mobility due to the presence of flagella. It thrives optimally at a temperature of 37°C, within a mesophilic range. The ecological habitat of EuSCAPE_EE009 is predominantly host-associated, indicating its reliance on living hosts for survival. It has been identified in a wide array of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other vertebrates and metazoans, suggesting a broad ecological niche. As a free-living organism, it can also exist independently outside of host organisms. This strain has significant implications for human health, being associated with a range of serious infections, including bacteremia, pneumonia, urinary tract infections, and sepsis. The extensive list of health effects highlights its pathogenic potential, particularly in vulnerable populations. The presence of Klebsiella pneumoniae in diverse hosts underscores its adaptability and ability to thrive in various environments, which may contribute to its role as an opportunistic pathogen. The strain’s ability to cause a wide spectrum of infections in both humans and animals may be linked to its evolutionary success as a commensal and pathogenic organism in different ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_EE009

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_EE009
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_EE009 genome assembly,

Gene Summary

Adenine Count

1213207 bp

Thymine Count

1207717 bp

Guanine Count

1604184 bp

Cytosine Count

1620176 bp

Genome Length

5645284 bp

Protein-coding Genes

5135 genes

Non-Coding Genes

322 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trar/dksa family transcriptional regulatorSAMEA3499913_00810Not AvailableNegative808542 - 8087698345.01
Hypothetical proteinSAMEA3499913_00811Not AvailableNegative808769 - 8089938336.99
Hypothetical proteinSAMEA3499913_00812Not AvailableNegative809059 - 80943014213.0
Cell division blocking proteinSAMEA3499913_00813Not AvailableNegative809427 - 8096277290.03
Regulatory protein ciiSAMEA3499913_00814Not AvailableNegative809635 - 81014418388.2
Cro/ci family transcriptional regulatorSAMEA3499913_00815Not AvailableNegative810196 - 81054913215.0
CiSAMEA3499913_00816Not AvailablePositive810671 - 81153131112.4
Duf2511 domain-containing proteinSAMEA3499913_00817Not AvailablePositive811540 - 81187812226.4
IntegraseSAMEA3499913_00818Not AvailablePositive812674 - 81295210351.7
protein of uncharacterised function (duf2946)SAMEA3499913_00819Not AvailablePositive813168 - 81362616869.2

Displaying genes 31 – 40 of 5457 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total