Klebsiella pneumoniae strain EuSCAPE_FR078

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR078 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. It typically exists in host-associated habitats and can be observed in various arrangements, including chains, pairs, and singles. This strain possesses flagella, allowing for mobility, and has a mesophilic optimal growth temperature of 37°C, with a temperature range that supports its survival in warm-blooded hosts. K. pneumoniae EuSCAPE_FR078 has been identified as a pathogen of significant clinical concern, associated with a range of health effects in humans and other animals. Notable infections attributed to this strain include bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Additionally, it has been implicated in severe conditions such as sepsis, meningitis, and liver abscesses. Its pathogenicity extends beyond humans to various hosts, including domesticated animals such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as aquatic species like Danio rerio (zebrafish) and other metazoans. The strain's ability to thrive in diverse hosts indicates its ecological versatility and highlights the potential for zoonotic transmission. Given its widespread association with serious health issues, K. pneumoniae EuSCAPE_FR078 represents a critical focus for ongoing research into antimicrobial resistance and the dynamics of bacterial infections across different species. Understanding its interactions within various ecosystems may provide insights into controlling its spread and reducing the burden of infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR078

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR078
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR078 genome assembly,

Gene Summary

Adenine Count

1131108 bp

Thymine Count

1128142 bp

Guanine Count

1520733 bp

Cytosine Count

1511361 bp

Genome Length

5291344 bp

Protein-coding Genes

4709 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
marr family transcriptional regulatorSAMEA3500062_01502Not AvailablePositive1596214 - 159657013577.3
lipoproteinSAMEA3500062_01503Not AvailableNegative1596560 - 15967998481.36
Late control d family proteinSAMEA3500062_01504Not AvailableNegative1597359 - 159849841633.1
Tail sheath monomerSAMEA3500062_01505Not AvailablePositive1598653 - 159982542712.0
Major tail tube proteinSAMEA3500062_01506Not AvailablePositive1599825 - 160034018914.4
Tail proteinSAMEA3500062_01507Not AvailablePositive1600386 - 160070311303.7
Tail tape measure proteinSAMEA3500062_01508Not AvailablePositive1600848 - 1603823105204.0
Tail proteinSAMEA3500062_01509Not AvailablePositive1603838 - 160433518590.3
AttlNot AvailableNot AvailablePositive1601921 - 1601932Not Available
Tail fiber proteinSAMEA3500062_01512Not AvailableNegative1607606 - 160870338890.3

Displaying genes 61 – 70 of 5015 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total