Klebsiella pneumoniae strain EuSCAPE_FR070

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR070 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain exhibits a diverse cell arrangement, appearing in chains, pairs, and singles. It is motile and possesses flagella, which may contribute to its ability to colonize various environments. The habitat of EuSCAPE_FR070 is primarily host-associated, indicating a close relationship with living organisms, including humans (Homo sapiens) and a range of other hosts such as birds (Gallus gallus, Phasianidae), mammals (Sus scrofa, Canis lupus familiaris, Equidae), and fish (Danio rerio). This broad host range underscores its ecological adaptability. EuSCAPE_FR070 thrives optimally at 37°C, within the mesophilic temperature range, and it has a single replicon and a double membrane structure. The strain is known for its significant health impacts, leading to various infections including bacteremia, urinary tract infections, pneumonia, and several others, particularly in humans. Its pathogenicity highlights its role as an opportunistic pathogen, especially in immunocompromised individuals. The ability of Klebsiella pneumoniae strain EuSCAPE_FR070 to cause numerous infections suggests its potential to exploit various ecological niches within host organisms. This adaptability not only enhances its survival but also complicates treatment due to the variety of infections it can cause. Understanding its traits and interactions with hosts is crucial for developing effective strategies to manage infections associated with this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR070

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR070
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR070 genome assembly,

Gene Summary

Adenine Count

1180946 bp

Thymine Count

1187037 bp

Guanine Count

1594144 bp

Cytosine Count

1571924 bp

Genome Length

5534051 bp

Protein-coding Genes

5023 genes

Non-Coding Genes

211 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Virion morphogenesis proteinSAMEA3500056_03233Not AvailablePositive3477036 - 347748217196.8
Baseplate assembly protein vSAMEA3500056_03234Not AvailablePositive3477551 - 347812920917.7
Phage baseplate assembly proteinSAMEA3500056_03235Not AvailablePositive3478126 - 347848512949.4
Baseplate assembly proteinSAMEA3500056_03236Not AvailablePositive3478472 - 347938032542.6
Tail protein iSAMEA3500056_03237Not AvailablePositive3479373 - 347997822525.8
Variable tail fiber proteinSAMEA3500056_03238Not AvailablePositive3479975 - 348139648942.1
Tail sheath proteinSAMEA3500056_03239Not AvailablePositive3482020 - 348319242380.2
Major tail tube proteinSAMEA3500056_03240Not AvailablePositive3483202 - 348371718862.4
Tail assembly proteinSAMEA3500056_03241Not AvailablePositive3483772 - 348407410899.5
Tail tape measure proteinSAMEA3500056_03242Not AvailablePositive3484201 - 3487278109005.0

Displaying genes 31 – 40 of 5234 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total