Klebsiella pneumoniae strain EuSCAPE_EE006

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_EE006 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain is notable for its capacity to exist in various cellular arrangements, including chains, pairs, and singles. It has a mesophilic optimal growth temperature of 37°C and possesses flagella, indicating mobility. K. pneumoniae strain EuSCAPE_EE006 is associated with a wide range of hosts, primarily affecting Homo sapiens and various animal species, including Gallus gallus, Danio rerio, and Sus scrofa, among others. This diverse host range highlights its ecological versatility and potential for zoonotic transmission. The strain is implicated in numerous health complications, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. These health effects underscore its significance as a human pathogen, particularly in hospital settings, leading to severe conditions such as sepsis and neonatal infections. K. pneumoniae strain EuSCAPE_EE006 is characterized as free-living, with a biotic relationship that allows it to thrive in host-associated environments. Its pathogenicity towards humans is a critical concern, as it can lead to serious medical conditions and complications, particularly in immunocompromised individuals. The presence of only one replicon and two membranes suggests a stable genomic structure, which may contribute to its adaptability and survival in various environments. Understanding the traits and health implications associated with K. pneumoniae strain EuSCAPE_EE006 can inform public health strategies and improve infection control measures in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_EE006

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_EE006
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_EE006 genome assembly,

Gene Summary

Adenine Count

1199476 bp

Thymine Count

1197552 bp

Guanine Count

1602625 bp

Cytosine Count

1607452 bp

Genome Length

5607105 bp

Protein-coding Genes

5057 genes

Non-Coding Genes

325 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cellulose synthase catalytic subunitSAMEA3499910_04011Not AvailableNegative4229313 - 423142479460.5
cellulose synthase, putativeSAMEA3499910_04012Not AvailableNegative4231444 - 423223528906.5
uncharacterised proteinSAMEA3499910_04013Not AvailableNegative4232237 - 423277618744.9
dipeptide transport atp-binding protein dppfSAMEA3499910_04014Not AvailableNegative4233292 - 423430537676.9
dipeptide transport atp-binding protein dppdSAMEA3499910_04015Not AvailableNegative4234302 - 423528535766.5
dipeptide transport system permease dppcSAMEA3499910_04016Not AvailableNegative4235296 - 423619832198.3
dipeptide transport system permease dppbSAMEA3499910_04017Not AvailableNegative4236208 - 423722737421.5
periplasmic dipeptide transport proteinSAMEA3499910_04018Not AvailableNegative4237362 - 423896960147.6
pts system proteinSAMEA3499910_04019Not AvailableNegative4240021 - 424032311331.6
pts system proteinSAMEA3499910_04020Not AvailableNegative4240421 - 424174348198.3

Displaying genes 4151 – 4160 of 5382 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total