Klebsiella pneumoniae strain EuSCAPE_FR045

Klebsiella pneumoniae strain EuSCAPE_FR045 is a significant pathogen primarily associated with human infections. This Gram-negative bacterium is rod-shaped, capable of mobility due to the presence of flagella, and exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. It typically thrives at an optimal temperature of 37°C within a mesophilic range. K. pneumoniae strain EuSCAPE_FR045 is known for its diverse pathogenic potential, causing a variety of serious health issues, including bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. Other notable conditions include liver abscesses, meningitis, wound infections, sepsis, and neonatal sepsis, underscoring its clinical relevance and impact on public health. This strain has a complex biotic relationship, being free-living but also capable of infecting multiple hosts, including Homo sapiens and various animal species such as Gallus gallus, Danio rerio, and Sus scrofa. The ability to infect a wide range of hosts suggests a versatile ecological niche for K. pneumoniae, allowing it to adapt and thrive in various environments. With a single replicon and two membranes, EuSCAPE_FR045's cellular structure supports its survival and pathogenic capabilities. Understanding the ecological and biological characteristics of this strain is critical for developing effective treatment strategies and mitigating its transmission, especially given its association with significant health outcomes in both humans and animals.