Klebsiella pneumoniae strain EuSCAPE_FR047

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR047 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism as a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, and singles, and is motile due to the presence of flagella. It thrives optimally at 37°C, falling within the mesophilic temperature range. This strain is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other species from both the Metazoa and Viridiplantae kingdoms. It has been linked to a wide array of health issues in humans, such as bacteremia, urinary tract infections, pneumonia, and more severe conditions like sepsis and meningitis. The bacterium’s pathogenicity is particularly notable in humans, where it can lead to serious complications, including pyogenic liver abscesses and neonatal sepsis. Klebsiella pneumoniae strain EuSCAPE_FR047 is nonsporulating and possesses a single replicon and two membranes, typical of Gram-negative bacteria. Its biotic relationship is categorized as free-living, indicating a level of environmental adaptability. The ecological insight from the data highlights the strain's significant role in human health and disease, underscoring its pathogenic potential across various infections. Its adaptability to different hosts and environments suggests that it may serve as a reservoir for antibiotic resistance, posing challenges to public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR047

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR047
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR047 genome assembly,

Gene Summary

Adenine Count

1246101 bp

Thymine Count

1247951 bp

Guanine Count

1637249 bp

Cytosine Count

1657995 bp

Genome Length

5789296 bp

Protein-coding Genes

5080 genes

Non-Coding Genes

417 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugal transfer pilin chaperone traqSAMEA3500032_05055Not AvailableNegative5387475 - 53877148991.16
conjugal pilus assembly protein trafSAMEA3500032_05056Not AvailableNegative5387725 - 538847728356.0
uncharacterised proteinSAMEA3500032_05057Not AvailableNegative5388498 - 538882412647.2
uncharacterised proteinSAMEA3500032_05058Not AvailableNegative5388837 - 53890859419.58
conjugal transfer protein trbeSAMEA3500032_05059Not AvailableNegative5389063 - 53893179527.68
type-f conjugative transfer system mating-pair stabilization protein tranSAMEA3500032_05060Not AvailableNegative5389349 - 539130470722.5
conjugal transfer pilus assembly protein trbcSAMEA3500032_05061Not AvailableNegative5391363 - 539201023677.0
uncharacterised proteinSAMEA3500032_05062Not AvailablePositive5392218 - 53923254249.33
conjugal transfer pilus assembly protein trauSAMEA3500032_05063Not AvailableNegative5392286 - 539327536380.9
uncharacterised proteinSAMEA3500032_05064Not AvailableNegative5393272 - 539367315988.5

Displaying genes 5181 – 5190 of 5497 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total